Evidence map›Paper›PMID 34078724›Full record

ArticleSaudi medical journal2021

The combinatorial use of propofol-fentanyl-ketamine for sedoanalgesia in patients undergoing urological procedures.

Abdelkarim S Aloweidi, Sami A Abu-Halaweh, Ghazi M Al-Edwan, Saddam H Al Demour, Laith T Abu Mahfuz, Osama N Noubani, Mohammad M Al Rwaidi, Isam K Bsisu, Mohammad M Abufaraj

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In one paragraph

Article in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Abdelkarim S AloweidiFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Sami A Abu-HalawehFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Ghazi M Al-EdwanFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Saddam H Al DemourFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Laith T Abu MahfuzFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Osama N NoubaniFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Mohammad M Al RwaidiFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Isam K BsisuFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
Mohammad M AbufarajFrom the Department of Anesthesia and Intensive Care (Aloweidi, Abu-Halaweh, Abu Mahfuz, Noubani, Al Rwaidi, Bsisu); from the Division of Urology, Department of Special Surgery (Al-Edwan, AL Demour, Abufaraj), School of Medicine, The University of Jordan, Amman, Jordan; and from the Department of Urology (Abufaraj), Medical University of Vienna, Vienna, Austria.
University of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare sedoanalgesia achieved using propofol-fentanyl-ketamine (PFK) combination with general anesthesia (GA) in terms of safety, hemodynamic stability, and perioperative complications.

methodsPatients in the GA group were anesthetized using fentanyl (2 μg kg-1) and propofol (2 mg kg-1). The PFK group was anesthetized using a mixture of which each one ml contains 0.005 mg of fentanyl, 5 mg of propofol, 5 mg of ketamine, and 2 mg of lidocaine. Patients received an initial dose of 0.05 ml kg-1, followed by 0.05 mg kg-1 60 seconds later. Maintenance boluses of 0.025 ml kg-1 were administered every 3-5 minutes. Respiration occurred spontaneously through a simple face mask with 3 L min-1 O

resultsThe GA group had 37 (37%) patients develop hypotensive episodes, compared to one (1%) episode in the PFK group (

conclusionThe PFK combination herein described is safe, effective, and provides intraoperative hemodynamic stability in patients with multiple comorbidities undergoing urological procedures.

Indexed as

KetaminePropofolAnesthetics, IntravenousFentanylHemodynamicsHumansAnesthetics, IntravenousFentanylKetaminePropofolfentanylgeneral anesthesiaketaminepropofolurological procedures

Identifiers

PMID34078724
PMCPMC9149711
OpenAlexW3164989035

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.