Evidence map›Paper›PMID 34078666›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Glia-derived temporal signals orchestrate neurogenesis in the

Mengying Yang, Honglei Wang, Changyan Chen, Shiping Zhang, Mengxiao Wang, Bhagyashree Senapati, Shuhua Li, Shuanglong Yi, Linfang Wang, Min Zhang and 5 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Autophagy · 2025
    Article
  4. Review
  5. The making of the Drosophila mushroom body.Frontiers in physiology · 2023
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Mengying YangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Honglei WangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID 0000-0002-2764-8988
Changyan ChenDepartment of Anatomy and Neurobiology, School of Medicine, Tongji University, Shanghai 200092, China.
Shiping ZhangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Mengxiao WangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Bhagyashree SenapatiInstitute of Molecular Biology, Academia Sinica, Taipei, 115, Taiwan.ORCID 0000-0002-2901-572X
Shuhua LiSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Shuanglong YiSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Linfang WangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Min ZhangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Shuai YinDepartment of Anatomy and Neurobiology, School of Medicine, Tongji University, Shanghai 200092, China.ORCID 0000-0002-2045-9893
Yijing HeDepartment of Anatomy and Neurobiology, School of Medicine, Tongji University, Shanghai 200092, China.
Lei XueInstitute of Intervention Vessel, Shanghai 10th People's Hospital, Shanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Tongji University, Shanghai 200092, China.
Suewei LinInstitute of Molecular Biology, Academia Sinica, Taipei, 115, Taiwan.ORCID 0000-0001-7079-7818
Margaret S HoSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China; margareth@shanghaitech.edu.cn.ORCID 0000-0002-2387-7564
ShanghaiTech University · CNTongji University · CNInstitute of Molecular Biology, Academia Sinica · TWChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrinsic mechanisms such as temporal series of transcription factors orchestrate neurogenesis from a limited number of neural progenitors in the brain. Extrinsic regulations, however, remain largely unexplored. Here we describe a two-step glia-derived signal that regulates neurogenesis in the

Indexed as

Cell CommunicationCell ProliferationNeurogenesisAnimalsDrosophila melanogasterDrosophila ProteinsMushroom BodiesNeurogliaDrosophila Proteinsgliamushroom bodyneurogenesis

Identifiers

PMID34078666
PMCPMC8201942
OpenAlexW3165544645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.