ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale2021
Micro-CT imaging of Thiel-embalmed and iodine-stained human temporal bone for 3D modeling.
Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- An in situ non-contact 3D microscopic measurement system for temporal bone anatomy based on stereo imaging.Scientific reports · 2026Article
- The spinal consequences of HT-2 toxin and selenium deficiency during bone maturation in mice.Mycotoxin research · 2025Article
- Design and optimization of auditory prostheses using the finite element method: a narrative review.Annals of translational medicine · 2022Review
- Validated Ossicular Measurements on High-Resolution Computed Tomography (CT) in Live and Cadaveric Temporal Bones.Cureus · 2022Article
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5 authors.
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Abstract
introductionThis pilot study explores whether a human Thiel-embalmed temporal bone is suitable for generating an accurate and complete data set with micro-computed tomography (micro-CT) and whether solid iodine-staining improves visualization and facilitates segmentation of middle ear structures.
methodsA temporal bone was used to verify the accuracy of the imaging by first digitally measuring the stapes on the tomography images and then physically under the microscope after removal from the temporal bone. All measurements were compared with literature values. The contralateral temporal bone was used to evaluate segmentation and three-dimensional (3D) modeling after iodine staining and micro-CT scanning.
resultsThe digital and physical stapes measurements differed by 0.01-0.17 mm or 1-19%, respectively, but correlated well with the literature values. Soft tissue structures were visible in the unstained scan. However, iodine staining increased the contrast-to-noise ratio by a factor of 3.7 on average. The 3D model depicts all ossicles and soft tissue structures in detail, including the chorda tympani, which was not visible in the unstained scan.
conclusionsMicro-CT imaging of a Thiel-embalmed temporal bone accurately represented the entire anatomy. Iodine staining considerably increased the contrast of soft tissues, simplified segmentation and enabled detailed 3D modeling of the middle ear.
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