Evidence map›Paper›PMID 34078362›Full record

Trial reportBMC medicine2021

Promoting physical activity in a multi-ethnic population at high risk of diabetes: the 48-month PROPELS randomised controlled trial.

Kamlesh Khunti, Simon Griffin, Alan Brennan, Helen Dallosso, Melanie J Davies, Helen C Eborall, Charlotte L Edwardson, Laura J Gray, Wendy Hardeman, Laura Heathcote and 6 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Kamlesh Khunti *Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK. kk22@le.ac.uk.ORCID 0000-0003-2343-7099
Simon GriffinMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Alan BrennanSchool of Health and Related Research, University of Sheffield, Sheffield, UK.
Helen DallossoNIHR Applied Research Collaboration - East Midlands, Leicester, UK.
Melanie J DaviesDiabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK.
Helen C EborallUsher Institute, University of Edinburgh, Edinburgh, UK.
Charlotte L EdwardsonDiabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK.
Laura J GrayBiostatistics Research Group, Department of Health Sciences, University of Leicester, Leicester, UK.
Wendy HardemanSchool of Health Sciences, University of East Anglia, Norwich, UK.
Laura HeathcoteSchool of Health and Related Research, University of Sheffield, Sheffield, UK.
Joe HensonDiabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK.
Daniel PollardSchool of Health and Related Research, University of Sheffield, Sheffield, UK.
Stephen J SharpMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
Stephen SuttonBehavioural Science Group, Primary Care Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Jacqui TroughtonLeicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, UK.
Tom Yates *Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester, UK.
University of Leicester · GBUniversity of Cambridge · GBUniversity of Sheffield · GBUniversity Hospitals of Leicester NHS Trust · GBUniversity of East Anglia · GBUniversity of Edinburgh · GB

Funding

Medical Research Council MC_UU_00006/6
6 · The paper itself

Abstract

backgroundPhysical activity is associated with a reduced risk of type 2 diabetes and cardiovascular disease but limited evidence exists for the sustained promotion of increased physical activity within diabetes prevention trials. The aim of the study was to investigate the long-term effectiveness of the Walking Away programme, an established group-based behavioural physical activity intervention with pedometer use, when delivered alone or with a supporting mHealth intervention.

methodsThose at risk of diabetes (nondiabetic hyperglycaemia) were recruited from primary care, 2013-2015, and randomised to (1) Control (information leaflet); (2) Walking Away (WA), a structured group education session followed by annual group-based support; or (3) Walking Away Plus (WAP), comprising WA annual group-based support and an mHealth intervention delivering tailored text messages supported by telephone calls. Follow-up was conducted at 12 and 48 months. The primary outcome was accelerometer measured ambulatory activity (steps/day). Change in primary outcome was analysed using analysis of covariance with adjustment for baseline, randomisation and stratification variables.

resultsOne thousand three hundred sixty-six individuals were randomised (median age = 61 years, ambulatory activity = 6638 steps/day, women = 49%, ethnic minorities = 28%). Accelerometer data were available for 1017 (74%) individuals at 12 months and 993 (73%) at 48 months. At 12 months, WAP increased their ambulatory activity by 547 (97.5% CI 211, 882) steps/day compared to control and were 1.61 (97.5% CI 1.05, 2.45) times more likely to achieve 150 min/week of moderate-to-vigorous physical activity. Differences were not maintained at 48 months. WA was no different to control at 12 or 48 months. Secondary anthropometric and health outcomes were largely unaltered in both intervention groups apart from small reductions in body weight in WA (~ 1 kg) at 12- and 48-month follow-up.

conclusionsCombining a pragmatic group-based intervention with text messaging and telephone support resulted in modest changes to physical activity at 12 months, but changes were not maintained at 48 months.

trial registrationISRCTN 83465245 (registered on 14 June 2012).

Indexed as

Diabetes Mellitus, Type 2Text MessagingActigraphyExerciseFemaleHumansMiddle AgedWalkingDiabetes preventionGroup-based interventionmHealthNon-diabetic hyperglycaemiaPedometerPhysical activityRandomised controlled trial

Identifiers

PMID34078362
PMCPMC8173914
OpenAlexW3165548082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.