ArticleBMC genomics2021
Metagenomic diagnosis of severe psittacosis using multiple sequencing platforms.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Pneumonia with BALF Detection ofInfection and drug resistance · 2026Article
- HTS and PCR Methods Are the Most Used in the Diagnosis of Aspergillosis: Advantages over Other Molecular Methods.Journal of fungi (Basel, Switzerland) · 2025Review
- Pneumonia Caused byInternational medical case reports journal · 2024Article
- Compare Clinical Characteristics of Psittacosis Pneumonia in 35 Patients and of Non Psittacosis Bacterial Pneumonia in 46 Patients.Infection and drug resistance · 2024Article
- Case Report of SevereInternational medical case reports journal · 2024Article
- Psittacosis: An Underappreciated and Often Undiagnosed Disease.Pathogens (Basel, Switzerland) · 2023Review
- Application of nanopore adaptive sequencing in pathogen detection of a patient withFrontiers in cellular and infection microbiology · 2023Article
- Chlamydia Psittaci Pneumonia-Induced Myocarditis: A Case Report.Infection and drug resistance · 2023Article
- Diagnosis by metagenomic next-generation sequencing of invasive pulmonary aspergillosis in an infant with chronic granulomatous disease.Respiratory medicine case reports · 2023Article
- Metagenomic next-generation sequencing for the diagnosis of Chlamydia psittaci pneumonia.The clinical respiratory journal · 2022Article
- Metagenomic next-generation sequencing identified psittacosis among poultry processing workers in Shandong Province, China.Infectious medicine · 2022Article
- Case Report: AFrontiers in public health · 2022Article
- Clinical value of metagenomic next-generation sequencing by Illumina and Nanopore for the detection of pathogens in bronchoalveolar lavage fluid in suspected community-acquired pneumonia patients.Frontiers in cellular and infection microbiology · 2022Article
- Clinical, radiological and pathological characteristics of moderate to fulminant psittacosis pneumonia.PloS one · 2022Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundChlamydia psittaci is an avian pathogen that can cause lethal human infections. Diagnosis of C. psittaci pneumonia is often delayed due to nonspecific clinical presentations and limited laboratory diagnostic techniques.
resultsThe MinION platform established the diagnosis in the shortest time, while BGISEQ-500 generated additional in-depth sequence data that included the rapid characterization of antibiotic susceptibility. Cytopathy appeared only in cell cultures of BALF. BALF yielded a higher bacterial load than sputum or blood, and may be the most suitable clinical specimen for the genomic diagnosis of severe pneumonia.
conclusionsThis study indicated that the benefits of metagenomic sequencing include rapid etiologic diagnosis of unknown infections and the provision of additional relevant information regarding antibiotic susceptibility. The continued optimization and standardization of sampling and metagenomic analysis promise to enhance the clinical utility of genomic diagnosis.
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