Evidence map›Paper›PMID 34078276›Full record

ArticleBMC geriatrics2021

The sex difference in gait speed among older adults: how do sociodemographic, lifestyle, social and health determinants contribute?

Lena D Sialino, Laura A Schaap, Sandra H van Oostrom, H Susan J Picavet, Johannes W R Twisk, W M Monique Verschuren, Marjolein Visser, Hanneke A H Wijnhoven

Abstract read
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. The INSPIRE-T longitudinal observational study centered on intrinsic capacity: baseline data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Area Deprivation Index and Frailty Among Older People With HIV.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Correlates of Gait Speed Among Older Adults From 6 Countries: Findings From the COSMIC Collaboration.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Changes in Physical Performance among Community-Dwelling Older Adults in Six Years.International journal of environmental research and public health · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lena D SialinoDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. l.d.sialino@vu.nl.
Laura A SchaapDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Sandra H van OostromCentre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
H Susan J PicavetCentre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Johannes W R TwiskDepartment of Clinical Epidemiology and Biostatistics, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
W M Monique VerschurenCentre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Marjolein VisserDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Hanneke A H WijnhovenDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study explores whether a sex difference in sensitivity to (strength of the association) and/or in exposure to (prevalence) determinants of gait speed contributes to the observed lower gait speed among older women compared to men.

methodsData from the Longitudinal Aging Study Amsterdam (LASA) were used. In total 2407 men and women aged 55-81 years were included, with baseline measurements in 1992/2002 and follow-up measurements every 3-4 years for 15/25 years. Multivariable mixed model analysis was used to investigate sex differences in sensitivity (interaction term with sex) and in exposure to (change of the sex difference when adjusted) socio-demographic, lifestyle, social and health determinants of gait speed.

resultsWomen had a 0.054 m/s (95 % CI: 0.076 - 0.033, adjusted for height and age) lower mean gait speed compared to men. In general, men and women had similar determinants of gait speed. However, higher BMI and lower physical activity were more strongly associated with lower gait speed in women compared to men (i.e. higher sensitivity). More often having a lower educational level, living alone and having more chronic diseases, pain and depressive symptoms among women compared to men also contributed to observed lower gait speed in women (i.e. higher exposure). In contrast, men more often being a smoker, having a lower physical activity and a smaller personal network size compared to women contributed to a lower gait speed among men (i.e. higher exposure).

conclusionsBoth a higher sensitivity and higher exposure to determinants of gait speed among women compared to men contributes to the observed lower gait speed among older women. The identified (modifiable) contributing factors should be taken into account when developing prevention and/or treatment strategies aimed to enhance healthy physical aging. This might require a sex-specific approach in both research and clinical practice, which is currently often lacking.

Indexed as

Sex CharacteristicsWalking SpeedAgedAgingFemaleGaitHumansLife StyleMalePhysical agingRisk factors

Identifiers

PMID34078276
PMCPMC8173843

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.