Evidence map›Paper›PMID 34078123›Full record

ArticleThyroid : official journal of the American Thyroid Association2021

CSPG4 Is a Potential Therapeutic Target in Anaplastic Thyroid Cancer.

Caitlin E Egan, Dessislava Stefanova, Adnan Ahmed, Vijay J Raja, Jessica W Thiesmeyer, Kevin J Chen, Jacques A Greenberg, Taotao Zhang, Bing He, Brendan M Finnerty and 6 more

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. B7-H3 and CSPG4-targeted CAR T cells as potent effectors in anaplastic thyroid cancer.Journal of experimental & clinical cancer research : CR · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Caitlin E EganDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Dessislava StefanovaDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-2460-9235
Adnan AhmedDepartment of Biochemistry, Weill Cornell Medicine, New York, New York, USA.
Vijay J RajaDepartment of Biochemistry, Weill Cornell Medicine, New York, New York, USA.
Jessica W ThiesmeyerDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Kevin J ChenDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Jacques A GreenbergDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Taotao ZhangDepartment of Pathology, and Weill Cornell Medicine, New York, New York, USA.
Bing HeDepartment of Pathology, and Weill Cornell Medicine, New York, New York, USA.
Brendan M FinnertyDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Rasa ZarnegarDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0003-2548-5764
Moonsoo M JinDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Theresa ScognamiglioDepartment of Pathology, and Weill Cornell Medicine, New York, New York, USA.
Noah DephoureDepartment of Biochemistry, Weill Cornell Medicine, New York, New York, USA.
Thomas FaheyDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.
Irene M MinDepartment of Surgery, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-1057-4804
Cornell University · US

Funding

Imaging-guided fine tuning of CAR T cell affinity to limit T cell cytotoxicity to tumor antigenR01CA217059 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI JIN, MOONSOO M. · 2018 to 2022
$2.6M
CAR T Cells for Advanced Thyroid CancerR01CA254035 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI JIN, MOONSOO M. · 2021 to 2024
$2.6M
NCI NIH HHS R01 CA217059NCI NIH HHS R01 CA254035
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene ExpressionGene Expression Regulation, NeoplasticMolecular Targeted TherapyAnimalsCD4-Positive T-LymphocytesCell Line, TumorChondroitin Sulfate Proteoglycan 4Chondroitin Sulfate ProteoglycansHLA-DQ AntigensHumansImmunotherapyMembrane ProteinsMiceMice, TransgenicPrognosisThyroid Carcinoma, AnaplasticChondroitin Sulfate Proteoglycan 4Chondroitin Sulfate ProteoglycansCSPG4 protein, humanHLA-DQ AntigensMembrane Proteinsanaplastic thyroid cancerCSPG4thyroid cancer

Identifiers

PMID34078123
PMCPMC8917884
OpenAlexW3165094908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.