ArticleEnvironmental pollution (Barking, Essex : 1987)2021
Early life multiple exposures and child cognitive function: A multi-centric birth cohort study in six European countries.
Article in Environmental pollution (Barking, Essex : 1987), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Sleep as a potential link between exposome, mental health and cognitive development in children and adolescents - a scoping review.Archives of public health = Archives belges de sante publique · 2026Pooled it
- Systematic Review: Neurodevelopmental Benefits of Active/Passive School Exposure to Green and/or Blue Spaces in Children and Adolescents.International journal of environmental research and public health · 2023Pooled it
- School-Based Interventions to Support Healthy Indoor and Outdoor Environments for Children: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Update of the human early life exposome (HELIX) cohort: a European population-based exposome cohort-cohort profile.BMJ open · 2026Article
- Early-Life Cumulative Intake of Ultra-Processed Foods and Subcortical Brain Volume at Age Six Years: A Prospective Cohort Study.The American journal of clinical nutrition · 2026Article
- Association between early life constituent-specific PMBMC medicine · 2026Article
- Exploring the exposome and unexplained variance in biological ageing - insights from a longitudinal twin study in adolescence and early adulthood.medRxiv : the preprint server for health sciences · 2026Article
- Early-Life Exposures, Neurodevelopment, and Health Outcomes: Protocol for a Birth Cohort Study.JMIR research protocols · 2026Article
- Short-term effect of PMScientific reports · 2026Article
- Dutch nationwide registry study to identify spatial, contextual and environmental inequalities in birth outcomes.BMJ public health · 2026Article
- The effect of the "exposome" on developmental brain health and cognitive outcomes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Impact of Residential Noise Exposure on Neurological Health: A Systematic Scoping Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- A novel approach to assessing the joint effects of mercury and fish consumption on neurodevelopment in the New Bedford Cohort.American journal of epidemiology · 2025Article
- World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain.Frontiers in pharmacology · 2025Review
- The effects of diabetes on attention function: a comparative analysis of children and adolescents with type 1 diabetes and their healthy peers.Frontiers in endocrinology · 2025Article
- Article
- Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food.EFSA journal. European Food Safety Authority · 2024Article
- Beyond the single-outcome approach: A comparison of outcome-wide analysis methods for exposome research.Environment international · 2023Article
- Epidemiological analysis of drinking water-type fluorosis areas and the impact of fluorosis on children's health in the past 40 years in China.Environmental geochemistry and health · 2023Article
- Breastfeeding is associated with the intelligence of school-age children in Mexico.Maternal & child nutrition · 2023Article
Corrections and comments
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Authors and funding
32 authors at 10 institutions in 9 countries.
Funding
Abstract
Epidemiological studies mostly focus on single environmental exposures. This study aims to systematically assess associations between a wide range of prenatal and childhood environmental exposures and cognition. The study sample included data of 1298 mother-child pairs, children were 6-11 years-old, from six European birth cohorts. We measured 87 exposures during pregnancy and 122 cross-sectionally during childhood, including air pollution, built environment, meteorology, natural spaces, traffic, noise, chemicals and life styles. The measured cognitive domains were fluid intelligence (Raven's Coloured Progressive Matrices test, CPM), attention (Attention Network Test, ANT) and working memory (N-Back task). We used two statistical approaches to assess associations between exposure and child cognition: the exposome-wide association study (ExWAS) considering each exposure independently, and the deletion-substitution-addition algorithm (DSA) considering all exposures simultaneously to build a final multiexposure model. Based on this multiexposure model that included the exposure variables selected by ExWAS and DSA models, child organic food intake was associated with higher fluid intelligence (CPM) scores (beta = 1.18; 95% CI = 0.50, 1.87) and higher working memory (N-Back) scores (0.23; 0.05, 0.41), and child fast food intake (-1.25; -2.10, -0.40), house crowding (-0.39; -0.62, -0.16), and child environmental tobacco smoke (ETS) (-0.89; -1.42, -0.35), were all associated with lower CPM scores. Indoor PM
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.