ArticleCell reports2021
Thalamic control of cortical dynamics in a model of flexible motor sequencing.
Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed.
- Tuft Dendrite Spikes Are Accompanied by Selective Input From Distinct Functional Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
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- Pretraining of Embodied Recurrent Networks Bridges the Gap Between Artificial and Cortical Neural Activities.Biomimetics (Basel, Switzerland) · 2026Article
- Distinct sensorimotor encoding in tuft dendrites and somata associated with action, correction, and learning.bioRxiv : the preprint server for biology · 2026Article
- Tuft dendrite spikes are accompanied by selective input from distinct functional networks.bioRxiv : the preprint server for biology · 2026Article
- Neural Circuit with Top-Down Inhibitory Feedback Outperforms Optimal Bayesian Integration in Multisensory Integration.Neuroscience bulletin · 2026Article
- Theory of temporal pattern learning in echo state networks.PNAS nexus · 2026Article
- Corticothalamic communication for action coordination in a skilled motor behavior.Nature neuroscience · 2026Article
- Attractor-Based Models for Sequences and Pattern Generation in Neural Circuits.Neural computation · 2026Article
- Shared somatosensory-motor neural population dynamics track motor recovery after stroke.bioRxiv : the preprint server for biology · 2026Article
- InputDSA : Demixing then comparing recurrent and externally driven dynamics.... International Conference on Learning Representations · 2026Article
- Reward-driven adaptation of movements requires strong recurrent basal ganglia-cortical loops.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Switching between Newly Learned Motor Skills.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Striatal ensembles specify and control granular forelimb actions.bioRxiv : the preprint server for biology · 2025Article
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- Article
- Embodied sensorimotor control: computational modeling of the neural control of movement.ArXiv · 2025Article
- Motor cortex flexibly deploys a high-dimensional repertoire of subskills.bioRxiv : the preprint server for biology · 2025Article
- A model of thalamo-cortical interaction for incremental binding in mental contour-tracing.PLoS computational biology · 2025Article
- Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors.
Funding
Abstract
The neural mechanisms that generate an extensible library of motor motifs and flexibly string them into arbitrary sequences are unclear. We developed a model in which inhibitory basal ganglia output neurons project to thalamic units that are themselves bidirectionally connected to a recurrent cortical network. We model the basal ganglia inhibitory patterns as silencing some thalamic neurons while leaving others disinhibited and free to interact with cortex during specific motifs. We show that a small number of disinhibited thalamic neurons can control cortical dynamics to generate specific motor output in a noise-robust way. Additionally, a single "preparatory" thalamocortical network can produce fast cortical dynamics that support rapid transitions between any pair of learned motifs. If the thalamic units associated with each sequence component are segregated, many motor outputs can be learned without interference and then combined in arbitrary orders for the flexible production of long and complex motor sequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.