Evidence map›Paper›PMID 34077698›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Reduced Proportion and Activity of Natural Killer Cells in the Lung of Patients with Idiopathic Pulmonary Fibrosis.

Tamara Cruz, Minxue Jia, John Sembrat, Tracy Tabib, Naomi Agostino, Tullia C Bruno, Dario Vignali, Pablo Sanchez, Robert Lafyatis, Ana L Mora and 2 more

Abstract readComparative StudyLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. The transcriptome of CD14The European respiratory journal · 2026
    Article
  4. Immunological mechanisms and therapeutic approaches in pulmonary fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Mechanisms and markers of lung ageing in health and disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  9. Review
  10. Review
  11. CD4Frontiers in immunology · 2025
    Review
  12. Article
  13. Article
  14. Lung-resident lymphocytes and their roles in respiratory infections and chronic respiratory diseases.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  15. Review
  16. Cell-cell interactions and communication dynamics in lung fibrosis.Chinese medical journal pulmonary and critical care medicine · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tamara CruzUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Minxue JiaUniversity of Pittsburgh Pittsburgh, Pennsylvania.
John SembratUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Tracy TabibUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Naomi AgostinoUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Tullia C BrunoUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Dario VignaliUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Pablo SanchezUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Robert LafyatisUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Ana L MoraUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Panayiotis BenosUniversity of Pittsburgh Pittsburgh, Pennsylvania.
Mauricio RojasUniversity of Pittsburgh Pittsburgh, Pennsylvania.ORCID 0000-0001-7340-4784

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
WILD TYPE P53-BASED ADJUVANT IMMUNOTHERAPY FOR SCCHNP50CA097190 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Greg M. Delgoffe · 2004 to 2026
$49.6M
Translational studies for identifying and targeting novel pathways in systemic sclerosis pathogenesisP50AR060780 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAFYATIS, ROBERT A. · 2011 to 2021
$14.9M
Mapping Age-Related Changes in the LungU01HL145550 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENOS, PANAGIOTIS V, FINKEL, TOREN · 2019 to 2022
$2.4M
Aging of Mesenchymal Stem Cells Missing Link in IPFR01HL123766 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROJAS, MAURICIO · 2015 to 2018
$1.9M
NCI NIH HHS P30 CA047904NCI NIH HHS P50 CA097190NHLBI NIH HHS R01 HL123766NHLBI NIH HHS U01 HL145550NIAMS NIH HHS P50 AR060780
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overAge FactorsCell DeathCellular SenescenceFemaleHumansIdiopathic Pulmonary FibrosisKiller Cells, NaturalMaleMiddle Aged

Identifiers

PMID34077698
PMCPMC8491266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.