ArticlePlant biotechnology journal2021
Genetic basis of kernel starch content decoded in a maize multi-parent population.
Article in Plant biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 57 citations in OpenAlex.
- Combined linkage mapping and association analysis reveal the genetic control of starch content in maize kernel.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genetic Dissection and Functional Validation ofInternational journal of molecular sciences · 2026Article
- Trehalose-6-phosphate phosphatase-mediated trehalose metabolism shapes sorghum grain domestication for brewing adaptation.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Comparative metabolomic analysis of leaves and kernels in wild type andFood chemistry. Molecular sciences · 2026Article
- Identification of transcription factors regulating starch biosynthesis in maize through integrated GWAS and transcriptomic analysis.BMC plant biology · 2026Article
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
- Dual-Layer Transcriptional-Protein Regulation by HvAP2-12 Represses HvAP2-18 Activity to Fine-Tune Barley Starch Synthesis.Plant biotechnology journal · 2025Article
- Genetic basis of grain protein and fat contents preliminarily decoded in a foxtail millet biparental recombinant inbred line population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Phenotypic characterization and genetic factor identification of starch content-related traits in foxtail millet (Setaria italica L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Discovery and validation of SSR marker-based QTL governing fresh pod yield in dolichos bean (Lablab purpureus L. Sweet).Scientific reports · 2025Article
- Review
- Novel candidate genes and genetic basis analysis of kernel starch content in tropical maize.BMC plant biology · 2025Article
- QTL-based dissection of three key quality attributes in maize using double haploid populations.Frontiers in plant science · 2025Article
- Genome-wide association study to identify the genomic loci associated with wheat heading date variation under autumn-sowing conditions.PloS one · 2025Article
- Photosynthetic performance of spring maize leaves and the development and formation of superior and inferior grains.Frontiers in plant science · 2025Article
- Calcium and Magnesium Regulation of Kernel Sugar Content in Maize: Role of Endogenous Hormones and Antioxidant Enzymes.International journal of molecular sciences · 2024Article
- GWAS and Meta-QTL Analysis of Kernel Quality-Related Traits in Maize.Plants (Basel, Switzerland) · 2024Article
- QTL Mapping and Candidate Gene Analysis for Starch-Related Traits in Tartary Buckwheat (International journal of molecular sciences · 2024Article
- Combining genome-wide association study and linkage mapping in the genetic dissection of amylose content in maize (Zea mays L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Exploring the phosphorus-starch content balance mechanisms in maize grains using GWAS population and transcriptome data.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
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Authors and funding
13 authors at 4 institutions in 1 country.
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Abstract
Starch is the most abundant storage carbohydrate in maize kernels and provides calories for humans and other animals as well as raw materials for various industrial applications. Decoding the genetic basis of natural variation in kernel starch content is needed to manipulate starch quantity and quality via molecular breeding to meet future needs. Here, we identified 50 unique single quantitative trait loci (QTLs) for starch content with 18 novel QTLs via single linkage mapping, joint linkage mapping and a genome-wide association study in a multi-parent population containing six recombinant inbred line populations. Only five QTLs explained over 10% of phenotypic variation in single populations. In addition to a few large-effect and many small-effect additive QTLs, limited pairs of epistatic QTLs also contributed to the genetic basis of the variation in kernel starch content. A regional association study identified five non-starch-pathway genes that were the causal candidate genes underlying the identified QTLs for starch content. The pathway-driven analysis identified ZmTPS9, which encodes a trehalose-6-phosphate synthase in the trehalose pathway, as the causal gene for the QTL qSTA4-2, which was detected by all three statistical analyses. Knockout of ZmTPS9 increased kernel starch content and, in turn, kernel weight in maize, suggesting potential applications for ZmTPS9 in maize starch and yield improvement. These findings extend our knowledge about the genetic basis of starch content in maize kernels and provide valuable information for maize genetic improvement of starch quantity and quality.
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