ArticleJapanese journal of radiology2021
Feasibility of perfusion and early-uptake
Article in Japanese journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Dual-phase multiobjective Bayesian optimization method for estimating hepatocellular carcinoma dynamics parameters from PET/CT scans.Quantitative imaging in medicine and surgery · 2025Article
- The impacts of time of echo (TE) and time of repetition (TR) on diffusion-derived 'vessel density' (DDVD) measurement: examples of liver, spleen, and hepatocellular carcinoma.Quantitative imaging in medicine and surgery · 2025Article
- A prior information-based multi-population multi-objective optimization for estimatingBMC medical imaging · 2025Article
- Dynamic FDG PET/CT imaging: quantitative assessment, advantages and application in the diagnosis of malignant solid tumors.Frontiers in oncology · 2025Review
- KineticEJNMMI physics · 2024Article
- From FDG and beyond: the evolving potential of nuclear medicine.Annals of nuclear medicine · 2023Review
- Clinical applications of artificial intelligence in liver imaging.La Radiologia medica · 2023Review
- Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model.Insights into imaging · 2023Article
- Dynamic chaotic gravitational search algorithm-based kinetic parameter estimation of hepatocellular carcinoma onBMC medical imaging · 2022Article
- Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function.Frontiers in physiology · 2021Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
purposePET enables a concurrent evaluation of perfusion status and metabolic activity. We aimed to evaluate the feasibility of perfusion and early-uptake MATERIALS AND
methodsData from 5 min dynamic PET/CT and conventional PET/CT scans were retrospectively collected from 17 pathologically diagnosed HCCs. Parameters such as hepatic arterial blood flow (Fa), portal vein blood flow (Fv), total blood flow (F), hepatic arterial perfusion index (HPI), portal vein perfusion index (PPI), blood volume (BV), extracellular mean transit time (MTT) and intracellular uptake rate (Ki) were calculated. Fa, HPI, MTT and Ki images were generated and used to identify HCC.
resultsCompared with the surrounding liver tissue, HCCs showed significant increases in Fa, HPI, Ki and the maximum standard uptake value (SUVmax) (all P < 0.001) and significant reductions in Fv (P < 0.05) and PPI (P < 0.001). F, BV and MTT (all P > 0.05) did not differ significantly between HCCs and the surrounding liver tissue. Perfusion and early-uptake PET/CT increased the positivity rate of HCCs from 52.9% with conventional PET/CT alone to 88.2% with the combined method (P < 0.05).
conclusionsPerfusion and early-uptake PET/CT are feasible for diagnosing HCC and provide added functional information to enhance diagnostic performance.
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