ArticleEuropean radiology2021
Assessment of thoracic disk herniation by using virtual noncalcium dual-energy CT in comparison with standard grayscale CT.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Quantification of intervertebral disc degeneration using dual-energy computed tomography collagen maps: a comparative study with MRI Pfirrmann grading.Scientific reports · 2026Article
- Detection of lumbar disc herniation and degeneration using photon-counting detector CT with virtual non-calcium imaging.European radiology · 2026Article
- Spectral CT electron density for evaluation of lumbar intervertebral disk degeneration.PloS one · 2026Article
- Improved visualization of electron-density dual-energy computed tomography for lumbar disc disease over the standard gray-scale type and virtual noncalcium imaging.Quantitative imaging in medicine and surgery · 2025Article
- Using Key Predictors in an SVM Model for Differentiating Spinal Fractures and Herniated Intervertebral Discs in Preoperative Anesthesia Evaluation.Diagnostics (Basel, Switzerland) · 2024Article
- Assessment of thoracic disc degeneration using dual-energy CT-based collagen maps.European radiology experimental · 2024Article
- Quantitative evaluation of disc degeneration using dual-energy CT: advantages of R-VH, D-VH values and the IVNCa + CT model.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Value of CT-based radiomics in evaluating the response of bone metastases to systemic drug therapy in breast cancer patients.Thoracic cancer · 2024Article
- Diagnostic performance of dual-energy CT with electron-density reconstruction for lumbar disc herniation.SA journal of radiology · 2024Article
- Dual-Energy CT in Cardiothoracic Imaging: Current Developments.Diagnostics (Basel, Switzerland) · 2023Review
- Multi-Contrast Differentiation by Dual-Energy Spectral CT Angiography in a Patient with Pulmonary Barium Granulomas.Diagnostics (Basel, Switzerland) · 2023Article
- Future of Low-Dose Computed Tomography and Dual-Energy Computed Tomography in Axial Spondyloarthritis.Current rheumatology reports · 2022Review
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17 authors.
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Abstract
objectivesTo determine the diagnostic accuracy of dual-energy CT (DECT) virtual noncalcium (VNCa) reconstructions for assessing thoracic disk herniation compared to standard grayscale CT.
methodsIn this retrospective study, 87 patients (1131 intervertebral disks; mean age, 66 years; 47 women) who underwent third-generation dual-source DECT and 3.0-T MRI within 3 weeks between November 2016 and April 2020 were included. Five blinded radiologists analyzed standard DECT and color-coded VNCa images after a time interval of 8 weeks for the presence and degree of thoracic disk herniation and spinal nerve root impingement. Consensus reading of independently evaluated MRI series served as the reference standard, assessed by two separate experienced readers. Additionally, image ratings were carried out by using 5-point Likert scales.
resultsMRI revealed a total of 133 herniated thoracic disks. Color-coded VNCa images yielded higher overall sensitivity (624/665 [94%; 95% CI, 0.89-0.96] vs 485/665 [73%; 95% CI, 0.67-0.80]), specificity (4775/4990 [96%; 95% CI, 0.90-0.98] vs 4066/4990 [82%; 95% CI, 0.79-0.84]), and accuracy (5399/5655 [96%; 95% CI, 0.93-0.98] vs 4551/5655 [81%; 95% CI, 0.74-0.86]) for the assessment of thoracic disk herniation compared to standard CT (all p < .001). Interrater agreement was excellent for VNCa and fair for standard CT (ϰ = 0.82 vs 0.37; p < .001). In addition, VNCa imaging achieved higher scores regarding diagnostic confidence, image quality, and noise compared to standard CT (all p < .001).
conclusionsColor-coded VNCa imaging yielded substantially higher diagnostic accuracy and confidence for assessing thoracic disk herniation compared to standard CT. KEY POINTS: • Color-coded VNCa reconstructions derived from third-generation dual-source dual-energy CT yielded significantly higher diagnostic accuracy for the assessment of thoracic disk herniation and spinal nerve root impingement compared to standard grayscale CT. • VNCa imaging provided higher diagnostic confidence and image quality at lower noise levels compared to standard grayscale CT. • Color-coded VNCa images may potentially serve as a viable imaging alternative to MRI under circumstances where MRI is unavailable or contraindicated.
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