Evidence map›Paper›PMID 34076699›Full record

ArticleJAMA network open2021

Association of Sex With Risk of 2-Year Revision Among Patients Undergoing Total Hip Arthroplasty.

Amanda Chen, Liz Paxton, Xinyan Zheng, Raquel Peat, Jialin Mao, Alexander Liebeskind, Laura E Gressler, Danica Marinac-Dabic, Vincent Devlin, Terri Cornelison and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Effects of Lumbar Fusion and Dual-Mobility Liners on Dislocation Rates Following Total Hip Arthroplasty in a Veteran Population.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2026
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Amanda ChenDepartment of Population Health Sciences, Weill Cornell College of Medicine, New York, New York.
Liz PaxtonKaiser Permanente, San Diego, California.
Xinyan ZhengDepartment of Population Health Sciences, Weill Cornell College of Medicine, New York, New York.
Raquel PeatOffice of Orthopedic Devices, Office of Product Evaluation and Quality, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.
Jialin MaoDepartment of Population Health Sciences, Weill Cornell College of Medicine, New York, New York.
Alexander LiebeskindDepartment of Population Health Sciences, Weill Cornell College of Medicine, New York, New York.
Laura E GresslerOffice of Clinical Evidence and Analysis, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.
Danica Marinac-DabicOffice of Clinical Evidence and Analysis, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.
Vincent DevlinOffice of Orthopedic Devices, Office of Product Evaluation and Quality, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.
Terri CornelisonHealth of Women Program, Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.
Art SedrakyanDepartment of Population Health Sciences, Weill Cornell College of Medicine, New York, New York.
Cornell University · USUnited States Food and Drug Administration · USCenter for Devices and Radiological Health · USKaiser Permanente San Diego Medical Center · US

Funding

FDA HHS U01 FD006936
6 · The paper itself

Abstract

Importance: The worldwide population is aging and includes more female individuals than male individuals, with higher rates of total hip arthroplasty (THA) among female individuals. Although research on this topic has been limited to date, several studies are currently under way. Objectives: To evaluate the association between sex and 2-year revision after THA. Design, Setting, and Participants: This cohort study used data from statewide databases in New York and California between October 1, 2015, and December 31, 2018. Patients 18 years or older with osteoarthritis who underwent THA and had sex recorded in the database were included in the analysis. Exposure: Total hip arthroplasty. Main Outcomes and Measures: The outcome of interest was the difference in early, all-cause revision surgery rates after primary THA between women and men. The association of sex with the revision rate was examined using Cox proportional hazards regression analysis. Results: Of 132 826 patients included in the study, 74 002 (55.7%) were women; the mean (SD) age was 65.9 (11.0) years, and the median follow-up time was 1.3 years (range, 0.0-3.0 years). The 2-year revision rate was 2.5% (95% CI, 2.4%-2.6%) among women and 2.1% (95% CI, 2.0%-2.2%) among men. After adjusting for demographic characteristics, comorbidities, and facility volume, a minimal clinically meaningful difference was observed in revision rates despite women having a higher risk of all-cause revision compared with men (hazard ratio, 1.16; 95% CI, 1.07-1.26; P < .001). The risk of revision was increased among women compared with men in the subgroup of patients who were younger than 55 years (hazard ratio, 1.47; 95% CI, 1.20-1.81; P < .001). Conclusions and Relevance: In this cohort study, no clinically meaningful difference in all-cause revision rates after primary THA was found between men and women at 2-year follow-up. The modest difference in the risk of revision between men and women in a small subgroup of patients younger than 55 years suggests that the risk of revision in this population should be studied further.

Indexed as

AdultAgedArthroplasty, Replacement, HipCohort StudiesFemaleHip ProsthesisHumansMaleMiddle AgedPostoperative ComplicationsProsthesis FailureReoperationRisk AssessmentRisk FactorsSex DistributionSex Factors

Identifiers

PMID34076699
PMCPMC8173374
OpenAlexW3165071528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.