Evidence map›Paper›PMID 34076484›Full record

ArticleJournal of virology2021

Influence of NKG2C Genotypes on HIV Susceptibility and Viral Load Set Point.

Khlood Alsulami, Naomi Bolastig, Franck P Dupuy, Tsoarello Mabanga, Louise Gilbert, Zahra Kiani, Jean-Pierre Routy, Julie Bruneau, Réjean Thomas, Cécile Tremblay and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Khlood AlsulamiResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Naomi BolastigResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Franck P DupuyResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Tsoarello MabangaResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Louise GilbertResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Zahra KianiResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Jean-Pierre RoutyResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Julie BruneauCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, Quebec, Canada.
Réjean ThomasClinique Médicale l'Actuel, Montréal, Quebec, Canada.
Cécile TremblayCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, Quebec, Canada.
Christos M TsoukasResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Jason SzaboInfectious Diseases, Immunology and Global Health Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Pierre CôtéClinique de Médecine Urbaine du Quartier Latin, Montréal, Quebec, Canada.
Benoit TrottierClinique de Médecine Urbaine du Quartier Latin, Montréal, Quebec, Canada.
Roger LeBlancClinique Médicale Opus, Montréal, Quebec, Canada.
Danielle RouleauDepartment of Microbiology, Infectiology, and Immunology, University of Montreal, Montreal, Quebec, Canada.
Nicole F BernardResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
investigators in the Montreal Primary HIV Infection cohort
McGill University Health Centre · CACentre Hospitalier de l’Université de Montréal · CAUniversité de Montréal · CA

Funding

Fonds de Recherche du Québec - Santé (FRQS) AIDS and Infectious Diseases NetworkGouvernement du Canada | Canadian Institutes of Health Research (CIHR) 148491
6 · The paper itself

Abstract

NKG2C is an activating NK cell receptor encoded by a gene having an unexpressed deletion variant. Cytomegalovirus (CMV) infection expands a population of NKG2C

Indexed as

AllelesCoinfectionCytomegalovirus InfectionsFemaleGene FrequencyGenetic Predisposition to DiseaseGenotypeHIV InfectionsHIV SeronegativityHumansKiller Cells, NaturalMaleNK Cell Lectin-Like Receptor Subfamily CViral LoadKLRC2 protein, humanNK Cell Lectin-Like Receptor Subfamily Cadaptive NK cellsHIV exposed seronegativeHIV load set pointhuman immunodeficiency virusinjection drug usersmen who have sex with menpeople living with HIV

Identifiers

PMID34076484
PMCPMC8312870
OpenAlexW3165063606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.