Evidence map›Paper›PMID 34076466›Full record

ArticlemBio2021

Outer Membrane Vesicles of Vibrio cholerae Protect and Deliver Active Cholera Toxin to Host Cells via Porin-Dependent Uptake.

Franz G Zingl, Himadri B Thapa, Martina Scharf, Paul Kohl, Anna M Müller, Stefan Schild

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
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  6. Article
  7. Outer membrane vesicles fromMicrobiology spectrum · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Outer membrane vesicles inMicrobial cell (Graz, Austria) · 2026
    Article
  13. Outer membrane vesicles fromFrontiers in microbiology · 2026
    Article
  14. Identification and characterization ofFrontiers in microbiology · 2026
    Article
  15. Review
  16. Review
  17. Review
  18. bioRxiv : the preprint server for biology · 2025
    Article
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Franz G ZinglInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Himadri B ThapaInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Martina ScharfInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Paul KohlInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Anna M MüllerInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
Stefan SchildInstitute of Molecular Biosciences, University of Graz, Graz, Austria.
University of Graz · AT

Funding

Austrian Science Fund FWF DOC 50
6 · The paper itself

Abstract

Outer membrane vesicles (OMVs) are an emerging research field due to their multifactorial composition and involvement in interspecies and intraspecies communication. Recent studies indicate that vesicle release by Gram-negative bacterial pathogens is increased during

Indexed as

AnimalsBacterial Outer Membrane ProteinsBiological TransportCaco-2 CellsCholera ToxinEpithelial CellsHT29 CellsHumansMiceMice, Inbred C57BLPorinsSecretory VesiclesVibrio choleraeVirulence FactorsBacterial Outer Membrane ProteinsCholera ToxinPorinsVirulence Factorscargocholera toxingastrointestinal tracthuman intestinal cellsinternalizationOmpTOmpUouter membrane vesiclesrhodaminetrypsinVibrio choleraevirulence

Identifiers

PMID34076466
PMCPMC8262896
OpenAlexW3165460729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.