Evidence map›Paper›PMID 34075780›Full record

ArticleJournal of the American Heart Association2021

Perceived Versus Objective Change in Walking Ability in Peripheral Artery Disease: Results from 3 Randomized Clinical Trials of Exercise Therapy.

Mary M McDermott, Lu Tian, Michael H Criqui, Luigi Ferrucci, Philip Greenland, Jack M Guralnik, Melina R Kibbe, Lingyu Li, Robert Sufit, Lihui Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Mary M McDermottDepartment of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Lu TianBiomedical Science Data Stanford University Palo Alto CA.
Michael H CriquiDepartment of Family Medicine and Public Health University of California La Jolla CA.
Luigi FerrucciDivision of Intramural Research National Institute on Aging Baltimore MD.
Philip GreenlandDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Jack M GuralnikDepartment of Epidemiology University of Maryland Baltimore MD.
Melina R KibbeDepartment of Surgery Division of Vascular and Endovascular Surgery University of North Carolina Chapel Hill NC.
Lingyu LiDepartment of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Robert SufitDepartment of Neurology Northwestern University Feinberg School of Medicine Chicago IL.
Lihui ZhaoDepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Tamar S PolonskyDepartment of Medicine University of Chicago IL.
Northwestern University · USNational Institute on Aging · USPalo Alto University · USUniversity of California System · USUniversity of Chicago · USUniversity of Maryland, Baltimore · USUniversity of North Carolina at Chapel Hill · US

Funding

PROgenitor Cell Release Plus Exercise To Improve Functional Performance In PADR01HL107510 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2011 to 2015
$5.6M
Improving Functioning in Peripheral Arterial DiseaseR01HL073351 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2003 to 2007
$4.9M
Low InTensity Exercise Intervention for Peripheral Artery Disease: The LITE TrialR01HL122846 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2015 to 2018
$3.0M
Increasing Activity in Peripheral Arterial DiseaseR01HL088589 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCDERMOTT, MARY MCGRAE · 2008 to 2011
$2.9M
NHLBI NIH HHS R01 HL073351NHLBI NIH HHS R01 HL088589NHLBI NIH HHS R01 HL107510NHLBI NIH HHS R01 HL122846
6 · The paper itself

Abstract

Background In people with lower-extremity peripheral artery disease, the effects of exercise on patient-reported outcomes remain unclear. Methods and Results Four hundred four people with peripheral artery disease in 3 clinical trials were randomized to exercise (N=205) or a control group (N=199) and completed the 6-minute walk and the Walking Impairment Questionnaire distance score (score 0-100, 100=best) at baseline and 6-month follow-up. Compared with the control group, exercise improved 6-minute walk distance by +39.8 m (95% CI, 26.8-52.8,

Indexed as

Exercise TherapyExercise TolerancePatient Reported Outcome MeasuresWalkingWalk TestAgedFemaleHumansIntermittent ClaudicationMaleMiddle AgedPeripheral Arterial DiseasePredictive Value of TestsRandomized Controlled Trials as TopicRecovery of FunctionReproducibility of Resultsexerciseintermittent claudicationpatient‐reported outcome measuresperipheral artery disease

Identifiers

PMID34075780
PMCPMC8477873
OpenAlexW3164117289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.