Evidence map›Paper›PMID 34075732›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Toward Mechanochromic Soft Material-Based Visual Feedback for Electronics-Free Surgical Effectors.

Goffredo Giordano, Mariacristina Gagliardi, Yu Huan, Marco Carlotti, Andrea Mariani, Arianna Menciassi, Edoardo Sinibaldi, Barbara Mazzolai

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Goffredo GiordanoCenter for Micro-BioRobotics, Italian Institute of Technology, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.ORCID 0000-0002-5844-1496
Mariacristina GagliardiNEST, Scuola Normale Superiore and Istituto Nanoscienze, Consiglio Nazionale delle Ricerche, Piazza S. Silvestro, 12, Pisa (PI), 56127, Italy.ORCID 0000-0002-5860-3141
Yu HuanThe BioRobotics Institute, Scuola Superiore Sant'Anna, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.
Marco CarlottiCenter for Micro-BioRobotics, Italian Institute of Technology, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.ORCID 0000-0001-8086-7613
Andrea MarianiThe BioRobotics Institute, Scuola Superiore Sant'Anna, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.
Arianna MenciassiThe BioRobotics Institute, Scuola Superiore Sant'Anna, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.
Edoardo SinibaldiCenter for Micro-BioRobotics, Italian Institute of Technology, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.ORCID 0000-0002-9755-3431
Barbara MazzolaiCenter for Micro-BioRobotics, Italian Institute of Technology, Viale Rinaldo Piaggio 34, Pontedera (PI), 56025, Italy.

Funding

European Union's Horizon 2020Marie Skłodowska-Curie 885881
6 · The paper itself

Abstract

A chromogenically reversible, mechanochromic pressure sensor is integrated into a mininvasive surgical grasper compatible with the da Vinci robotic surgical system. The sensorized effector, also featuring two soft-material jaws, encompasses a mechanochromic polymeric inset doped with functionalized spiropyran (SP) molecule, designed to activate mechanochromism at a chosen pressure and providing a reversible color change. Considering such tools are systematically in the visual field of the operator during surgery, color change of the mechanochromic effector can help avoid tissue damage. No electronics is required to control the devised visual feedback. SP-doping of polydimethylsiloxane (2.5:1 prepolymer/curing agent weight ratio) permits to modulate the mechanochromic activation pressure, with lower values around 1.17 MPa for a 2% wt. SP concentration, leading to a shorter chromogenic recovery time of 150 s at room temperature (25 °C) under green light illumination. Nearly three-times shorter recovery time is observed at body temperature (37 °C). To the best of knowledge, this study provides the first demonstration of mechanochromic materials in surgery, in particular to sensorize unpowered surgical effectors, by avoiding dramatic increases in tool complexity due to additional electronics, thus fostering their application. The proposed sensing strategy can be extended to further tools and scopes.

Indexed as

Feedback, SensoryVisual PerceptionColorEquipment DesignRobotic Surgical ProceduresUser-Computer Interfacebiomedicalmechanochromic graspermechanochromismminimally invasive surgeryspiropyransurgical graspervisual feedback

Identifiers

PMID34075732
PMCPMC8336492

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.