SynthesisJournal of cardiac surgery2021
Meta-analysis of surgical treatment for postinfarction left ventricular free-wall rupture.
Synthesis in Journal of cardiac surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Meta-analysis of surgical treatment for postinfarction left ventricular free-wall rupture.Journal of cardiac surgery · 2021Pooled it
- Subacute Left Ventricular Free-Wall Rupture After Thrombolysis: From Concealed Rupture on CT to Successful Surgical Patch Repair.Diagnostics (Basel, Switzerland) · 2026Article
- Mechanical Complications After Acute Myocardial Infarction: A Shock-Stage and Timing-Based Management Framework.Journal of clinical medicine · 2026Review
- Spontaneous cardiac rupture as the initial presentation of acute myeloid leukaemia complicated by malignant lactic acidosis: a case report.European heart journal. Case reports · 2026Article
- Article
- Management of Myocardial Infarction and the Role of Cardiothoracic Surgery.Journal of clinical medicine · 2024Review
- From Atherosclerotic Plaque to Myocardial Infarction-The Leading Cause of Coronary Artery Occlusion.International journal of molecular sciences · 2024Review
- Masquerade of an emergency: cardiac tamponade as a deceptive presentation of primary cardiac diffuse large b-cell lymphoma-a case report.European heart journal. Case reports · 2024Article
- Post-Myocardial Infarction (MI) Left Ventricular Free Wall Rupture Managed Conservatively.Cureus · 2024Article
- Left ventricular free wall rupture caused by myocardial ischemia without treatable atherosclerotic coronary disease: a case series.Journal of cardiothoracic surgery · 2024Article
- Surgical Outcome of Postinfarction Left Ventricular Free Wall Rupture.Texas Heart Institute journal · 2024Article
- Post-infarction Left Ventricular Free Wall Rupture Diagnosed by Contrast-Enhanced Computed Tomography: A Case Report.Cureus · 2024Article
- Impact of COVID-19 on incidence and outcomes of post-infarction mechanical complications in Europe.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Spontaneous Coronary Artery Dissection Complicated by Left Ventricular Free Wall Rupture in Turner Syndrome.JACC. Case reports · 2023Article
- Surgical repair of left ventricular free-wall rupture complicating acute myocardial infarction: a single-center 30 years of experience.Frontiers in cardiovascular medicine · 2023Article
- Acute myocardial infarction complicated by purulent pericarditis: A case report.Clinical case reports · 2023Article
- Surgical repair of post-infarction ventricular free-wall rupture in the Netherlands: data from a nationwide registry.Annals of cardiothoracic surgery · 2022Article
- Sutureless repair techniques for post-infarction left ventricular free wall rupture.Annals of cardiothoracic surgery · 2022Review
- Risk factors for cardiac rupture after acute ST-segment elevation myocardial infarction during the percutaneous coronary intervention era: a retrospective case-control study.Journal of thoracic disease · 2022Article
- Left Ventricular Free Wall Rupture After Acute Myocardial Reinfarction Due to In-Stent Thrombosis in COVID-19 Patient.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLeft ventricular free-wall rupture (LVFWR) is one of the most lethal complications after acute myocardial infarction (AMI). The optimal therapeutic strategy is controversial. The current meta-analysis sought to examine the outcome of patients surgically treated for post-AMI LVFWR.
methodsA comprehensive literature review was performed to identify articles reporting outcomes of subjects who underwent LVFWR surgical repair. The primary endpoint was operative mortality. A meta-analysis was performed to assess the associations of predefined variables of interest and clinical prognosis.
resultsOf the 3132 retrieved articles, 11 nonrandomized studies, enrolling a total of 363 patients, fulfilled the inclusion criteria and were included in this analysis. The mean age of patients was 68 years. The operative mortality rate was 32% (n = 115). Meta-analysis revealed reduced operative risk in patients with oozing type rupture, as compared to blowout type (risk ratios [RR]: 0.47; 95% confidence interval [CI]: 0.33-0.67; p < .0001); RR was also significantly reduced in subjects in whom LVFWR was treated with sutureless technique, as compared to those undergoing sutured repair (RR: 0.59; 95% CI: 0.41-0.83; p = .002). Increased risk of operative mortality was demonstrated in patients who required postoperative extracorporeal membrane oxygenation (ECMO) support (RR: 2.39; 95% CI: 1.59-3.60; p < .0001).
conclusionsSurgical treatment of postinfarction LVFWR has a high operative mortality rate. Blowout rupture, sutured repair and postoperative ECMO support are factors associated with increased risk of operative mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.