Evidence map›Paper›PMID 34075545›Full record

ReviewClinical journal of gastroenterology2021

Early gastric cancer with lanthanum deposition mucosa by endoscopic submucosal dissection: a case report and literature review.

Daisaku Fujimoto, Ai Miyagi, Ushio Tamura, Sayo Takahashi, Seiko Okushi, Junko Miyagi, Hirohisa Ogawa, Toshihito Tanahashi

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daisaku FujimotoDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan.
Ai MiyagiDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan.
Ushio TamuraDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan.
Sayo TakahashiDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan.
Seiko OkushiDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan.
Junko MiyagiDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan.
Hirohisa OgawaDepartment of Pathology and Laboratory Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15, Kuramoto-cho, Tokushima, 770-8503, Japan.
Toshihito TanahashiDepartment of Internal Medicine, Local Incorporated Administrative Agency, Tokushima Prefecture Naruto Hospital, 32 Kurosaki Aza Kotani Muya-cho, Naruto, Tokushima, 772‑8503, Japan. tanahashi@kuh.biglobe.ne.jp.ORCID http://orcid.org/0000-0002-9308-210X
Naruto, Tokushima Prefecture hospital · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lanthanum carbonate is used to prevent hyperphosphatemia in dialysis patients with chronic renal failure and generally recognized as poorly absorbed by the gastrointestinal tract. However, some clinical cases of lanthanum deposition in the stomach have been shown. In addition, few endoscopic images of lanthanum deposition have been reported, particularly with respect to early-stage gastric cancer. A 64-year-old man with 22 years history of dialysis was treated with lanthanum carbonate for 3 years. With screening esophagogastroduodenoscopy, he was diagnosed with intramucosal gastric cancer, surrounded by the specific endoscopic images of the lanthanum deposition, and underwent endoscopic submucosal dissection. Histopathologically, massive accumulations of macrophages containing fine, granular, eosinophilic materials were observed in the lamina propria. These eosinophilic depositions were present in the lamina propria of the non-tumor region, but not in that of the tumor region. The histological features were further identified as lanthanum phosphate deposition by scanning electron microscopy. This case indicates the clinical significance of lanthanum deposition associated with gastric cancer. It is further required to evaluate more endoscopic images of the gastric mucosa, especially intramucosal cancer, with lanthanum deposition.

Indexed as

Endoscopic Mucosal ResectionHyperphosphatemiaStomach NeoplasmsGastric MucosaHumansLanthanumMaleMiddle AgedLanthanumChronic renal failureEndoscopic submucosal dissectionGastric cancerLanthanum depositionScanning electron microscopy

Identifiers

PMID34075545
OpenAlexW3164780123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.