ArticleAnnals of biomedical engineering2021
The Functionally Grading Elastic and Viscoelastic Properties of the Body Region of the Knee Meniscus.
Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Mechanical Signatures of Tibiofemoral Cartilage Degeneration Identified by Unconfined Compression Testing: Implications for Early Osteoarthritis Risk in Athletes.Medicina (Kaunas, Lithuania) · 2026Article
- Inherently bioactive iron-chelating Poly (N-acryloyl 2-glycine)/chitosan hydrogel scaffolds orchestrating dual hypoxic-immune microenvironment for functional meniscus regeneration.Bioactive materials · 2025Article
- Structure-property relationships in fibrous meniscal tissue through image-based augmentation.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025Article
- Mechanics of knee meniscus results from precise balance between material microstructure and synovial fluid viscosity.PloS one · 2025Article
- Article
- The alteration of the structure and macroscopic mechanical response of porcine patellar tendon by elastase digestion.Frontiers in bioengineering and biotechnology · 2024Article
- Effect of molecular weight and tissue layer on solute partitioning in the knee meniscus.Osteoarthritis and cartilage open · 2023Article
- Region- and layer-specific investigations of the human menisci using SHG imaging and biaxial testing.Frontiers in bioengineering and biotechnology · 2023Article
- Tensile energy dissipation and mechanical properties of the knee meniscus: relationship with fiber orientation, tissue layer, and water content.Frontiers in bioengineering and biotechnology · 2023Article
- On the microstructural origin of brain white matter hydraulic permeability.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The knee meniscus is a highly porous structure which exhibits a grading architecture through the depth of the tissue. The superficial layers on both femoral and tibial sides are constituted by a fine mesh of randomly distributed collagen fibers while the internal layer is constituted by a network of collagen channels of a mean size of 22.14 [Formula: see text]m aligned at a [Formula: see text] inclination with respect to the vertical. Horizontal dog-bone samples extracted from different depths of the tissue were mechanically tested in uniaxial tension to examine the variation of elastic and viscoelastic properties across the meniscus. The tests show that a random alignment of the collagen fibers in the superficial layers leads to stiffer mechanical responses (E = 105 and 189 MPa) in comparison to the internal regions (E = 34 MPa). All regions exhibit two modes of relaxation at a constant strain ([Formula: see text] to 7.7 s, [Formula: see text] = 49.9 to 59.7 s).
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Registered trials
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