ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2021
High-resolution genome-wide association study and genomic prediction for disease resistance and cold tolerance in wheat.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 34 citations in OpenAlex.
- Agronomic Performance and Dual Resistance Evaluation to Powdery Mildew and Stripe Rust in 660 Wheat Germplasm Lines.Plants (Basel, Switzerland) · 2026Article
- Evaluation and association analysis of quality traits in Chinese winter wheat landraces on the Qinghai-Tibet Plateau.BMC plant biology · 2026Article
- GWAS-informed genomic selection for cold tolerance in pepper (Capsicum annuum L.).BMC plant biology · 2026Article
- OptimGS: a dual integrative genomic prediction framework for improving cold stress tolerance in wheat.Briefings in bioinformatics · 2026Article
- Genetic dissection of cold stress tolerance and yield potential under cold stress in nested synthetic wheat (Triticum aestivum L.) introgression libraries using multi-locus genome-wide association and haplotype analysis.Functional & integrative genomics · 2026Article
- Genetic control of wheat flour end-use quality and rheology by genome-wide association studies.The plant genome · 2026Article
- Wheat's war against stripe rust: Integrating host immunity, genomics and breeding for durable resistance.The plant genome · 2026Review
- Mining QTLs and candidate genes in bread wheat associated with kernel hardness through GWAS.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- TaWRKY115 enhances cold tolerance by weakening the expression of TaMYB4 on CBFs in common wheat.National science review · 2026Article
- Article
- Article
- Genome-wide association study of alkali tolerance at germination stage in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genome-wide association mapping and candidate genes analysis of high-throughput image descriptors for wheat frost tolerance.Stress biology · 2025Article
- Genome-wide association analysis of winter survival in a diverse Canadian winter wheat population.The plant genome · 2025Article
- FreezeNet: A Lightweight Model for Enhancing Freeze Tolerance Assessment and Genetic Analysis in Wheat.Plant phenomics (Washington, D.C.) · 2025Article
- Leveraging Automated Machine Learning for Environmental Data-Driven Genetic Analysis and Genomic Prediction in Maize Hybrids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Multi-trait ridge regression BLUP withFrontiers in plant science · 2025Article
- Cytological mapping of a powdery mildew resistance locus PmRc1 based on wheat-Roegneria ciliaris structural rearrangement library.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Bifunctional SnOMikrochimica acta · 2024Article
- Genome-wide atlas of rust resistance loci in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 5 institutions in 2 countries.
Funding
Abstract
key messageHigh-resolution genome-wide association study (GWAS) facilitated QTL fine mapping and candidate gene identification, and the GWAS based genomic prediction models were highly predictive and valuable in wheat genomic breeding. Wheat is a major staple food crop and provides more than one-fifth of the daily calories and dietary proteins for humans. Genome-wide association study (GWAS) and genomic selection (GS) for wheat stress resistance and tolerance related traits are critical to understanding their genetic architecture for improvement of breeding selection efficiency. However, the insufficient marker density in previous studies limited the utility of GWAS and GS in wheat genomic breeding. Here, we conducted a high-resolution GWAS for wheat leaf rust (LR), yellow rust (YR), powdery mildew (PM), and cold tolerance (CT) by genotyping a panel of 768 wheat cultivars using genotyping-by-sequencing. Among 153 quantitative trait loci (QTLs) identified, 81 QTLs were delimited to ≤ 1.0 Mb intervals with three validated using bi-parental populations. Furthermore, 837 stress resistance-related genes were identified in the QTL regions with 12 showing induced expression by YR and PM pathogens. Genomic prediction using 2608, 4064, 3907, and 2136 pre-selected SNPs based on GWAS and genotypic correlations between the SNPs showed high prediction accuracies of 0.76, 0.73, and 0.78 for resistance to LR, YR, and PM, respectively, and 0.83 for resistance to cold damage. Our study laid a solid foundation for large-scale QTL fine mapping, candidate gene validation and GS in wheat.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.