Evidence map›Paper›PMID 34075339›Full record

ArticleInformatics in medicine unlocked2021

Computational prediction of nimbanal as potential antagonist of respiratory syndrome coronavirus.

Aanuoluwa Eunice Adegbola, Olumide Samuel Fadahunsi, Abdulahi Alausa, Ayodeji Zabdiel Abijo, Toheeb Adewale Balogun, Taiwo Sarah Aderibigbe, Banjo Semire, Peter Ifeoluwa Adegbola

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Informatics in medicine unlocked, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aanuoluwa Eunice AdegbolaDepartment of Pure and Applied Chemistry, Faculty of Pure and Applied Sciences, Ladoke Akintola University of Technology, Nigeria.
Olumide Samuel FadahunsiDepartment of Biochemistry, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Nigeria.
Abdulahi AlausaDepartment of Biochemistry, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Nigeria.
Ayodeji Zabdiel AbijoDepartment of Anatomy, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Nigeria.
Toheeb Adewale BalogunDepartment of Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Nigeria.
Taiwo Sarah AderibigbeDepartment of Science Laboratory Technology, Biological Sciences, Microbiology Unit, the Oke Ogun Polytechnic Saki, Nigeria.
Banjo SemireDepartment of Pure and Applied Chemistry, Faculty of Pure and Applied Sciences, Ladoke Akintola University of Technology, Nigeria.
Peter Ifeoluwa AdegbolaDepartment of Biochemistry, Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Nigeria.
Ladoke Akintola University of Technology · NGAdekunle Ajasin University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high pathogenic nature of the Middle East Respiratory coronavirus (MER) and the associated high fatality rate demands an urgent attention from researchers. Because there is currently no approved drug for the management of the disease, research efforts have been intensified towards the discovery of a potent drug for the treatment of the disease. Papain Like protease (PLpro) is one of the key proteins involved in the viral replication. We therefore docked forty-six compounds already characterized from

Indexed as

DexamethasoneMedicinal plantsMolecular dynamicsNimbanalPapain like proteaseRespiratory syndrome coronavirus

Identifiers

PMID34075339
PMCPMC8161736
OpenAlexW3164986251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.