ArticleSpinal cord2022
Association of age-adjusted D-dimer with deep vein thrombosis risk in patients with spinal cord injury: a cross-sectional study.
Article in Spinal cord, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Risk Prediction Models for Preoperative Deep Vein Thrombosis in Older Patients with Hip Fracture: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Lower red blood cell count is a risk factor for higher D-dimer level in patients with spinal cord injury: A five year retrospective cross-sectional study.The journal of spinal cord medicine · 2026Observational
- Nonlinear relationship and threshold effect of D-dimer on preoperative deep vein thrombosis in patients with ankle fractures: a retrospective study.Frontiers in surgery · 2026Article
- Global Prevalence of Deep Vein Thrombosis in Patients with Spinal Cord Injury: A Systematic Review and Meta-Analysis.Neurotrauma reports · 2025Review
- Risk factors for postoperative DVT exacerbation or new DVT in patients with spinal cord injury complicated with cervical fracture.Frontiers in cardiovascular medicine · 2024Article
- Relationship Between the Systemic Immune-Inflammation Index and Deep Venous Thrombosis After Spinal Cord Injury: A Cross-Sectional Study.Journal of inflammation research · 2024Article
- D-dimer/fibrinogen ratio for the prediction of deep venous thrombosis after traumatic spinal cord injury.Spinal cord · 2023Article
- Risk factors for postoperative portal vein thrombosis in patients with hepatitis B liver cancer and its impact on mortality-a retrospective study.Translational cancer research · 2022Article
- Role of a new age-adjusted D-dimer cutoff value for preoperative deep venous thrombosis exclusion in elderly patients with hip fractures.Journal of orthopaedic surgery and research · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designArticle.
objectiveTo elucidate the association of age-adjusted D-dimer (AAD) with deep vein thrombosis (DVT) risk to lower limbs in patients with spinal cord injury (SCI).
settingRehabilitation Medicine Department of the First Affiliated Hospital of China University of Science and Technology.
methodsRetrospective analysis of 250 patients with SCI in the rehabilitation department from August 2018 to December 2021. Quartiles divided the D-dimer level into four groups to analyze the association between AAD level and DVT risk.
resultsAge was identified as a covariate of D-dimer and DVT risk. For non-adjusted model, when D-dimer increased by 1 mg/L, DVT risk increased 0.23-fold (P < 0.05); for minimally-adjusted model (adjusted for age), the risk increased 0.22-fold (P < 0.05); and for fully-adjusted model (adjusted for age, sex, pulmonary infection, degree, grades, and career), it increased 0.19-fold (P < 0.05). AAD had a curvilinear association with DVT risk, and the fold point was 1.9 mg/L (P < 0.05). When serum AAD level was <1.9 mg/L (K < 1.9), the estimated change in DVT risk was 3.34 (P < 0.05), and when serum AAD level was >1.9 mg/L (K > 1.9), the estimated change was 1.14 (P < 0.05). Urinary tract infection (UTI) and fibrinogen(tertile) had a interaction association with D-dimer level and DVT risk (P interaction < 0.05).
conclusionPatients with SCI who receive rehabilitation treatment with AAD level >1.9 mg/L need to be paid close attention to, especially those with UTI and high levels of fibrinogen.
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