Evidence map›Paper›PMID 34075141›Full record

ArticleScientific reports2021

Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ

Richard Kanyo, Md Ruhul Amin, Laszlo F Locskai, Danika D Bouvier, Alexandria M Olthuis, W Ted Allison, Declan W Ali

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploring Cannabinoid Effects Using Zebrafish (International journal of molecular sciences · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Zebrafish as an Animal Model in Cannabinoid Research.International journal of molecular sciences · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. In Vivo Evaluation ofPharmaceuticals (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Richard KanyoCentre for Prions and Protein Folding Disease, University of Alberta, Edmonton, AB, T6G 2M8, Canada.
Md Ruhul AminDepartment of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2E9, Canada.
Laszlo F LocskaiCentre for Prions and Protein Folding Disease, University of Alberta, Edmonton, AB, T6G 2M8, Canada.
Danika D BouvierDepartment of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2E9, Canada.
Alexandria M OlthuisDepartment of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2E9, Canada.
W Ted AllisonCentre for Prions and Protein Folding Disease, University of Alberta, Edmonton, AB, T6G 2M8, Canada.
Declan W AliDepartment of Biological Sciences, University of Alberta, Edmonton, AB, T6G 2E9, Canada. declan.ali@ualberta.ca.
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In light of legislative changes and the widespread use of cannabis as a recreational and medicinal drug, delayed effects of cannabis upon brief exposure during embryonic development are of high interest as early pregnancies often go undetected. Here, zebrafish embryos were exposed to cannabidiol (CBD) and Δ

Indexed as

OptogeneticsAnimalsBehavior, AnimalCannabidiolDose-Response Relationship, DrugDronabinolEmbryonic DevelopmentEmbryo, NonmammalianLocomotionZebrafishCannabidiolDronabinol

Identifiers

PMID34075141
PMCPMC8169761
OpenAlexW3164277227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.