Evidence map›Paper›PMID 34074789›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Genetic basis of variation in cocaine and methamphetamine consumption in outbred populations of

Brandon M Baker, Mary Anna Carbone, Wen Huang, Robert R H Anholt, Trudy F C Mackay

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Cocaine remodels mFrontiers in cellular neuroscience · 2026
    Article
  2. The use ofFrontiers in cell and developmental biology · 2026
    Review
  3. Article
  4. Bitter Sensing ProtectsThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  5. Article
  6. The genetic basis of incipient sexual isolation inProceedings. Biological sciences · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. The Use ofBiomedicines · 2022
    Review
  11. Article
  12. From single flies to many genes: UsingProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brandon M BakerDepartment of Genetics and Biochemistry, Clemson University, Greenwood, SC 29646.ORCID 0000-0003-3105-2308
Mary Anna CarboneThe Center for Integrated Fungal Research, North Carolina State University, Raleigh, NC 27695.ORCID 0000-0002-5086-2480
Wen HuangDepartment of Animal Science, Michigan State University, East Lansing, MI 48824.ORCID 0000-0001-6788-8364
Robert R H AnholtDepartment of Genetics and Biochemistry, Clemson University, Greenwood, SC 29646.ORCID 0000-0001-7196-8324
Trudy F C MackayDepartment of Genetics and Biochemistry, Clemson University, Greenwood, SC 29646; tmackay@clemson.edu.ORCID 0000-0002-2312-7245
Center for Human Genetics · USMichigan State University · USNorth Carolina State University · US

Funding

Genetics of Cocaine Sensitivity in DrosophilaU01DA041613 · NIDA · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Robert R. H Anholt, TRUDY F. MACKAY · 2017 to 2026
$4.9M
NIDA NIH HHS U01 DA041613
6 · The paper itself

Abstract

We used

Indexed as

Epistasis, GeneticPolymorphism, Single NucleotideQuantitative Trait LociSex CharacteristicsAnimalsCocaineDrosophila melanogasterDrosophila ProteinsFemaleGenome-Wide Association StudyHumansMaleMethamphetamineCocaineDrosophila ProteinsMethamphetamineadvanced intercross populationDrosophila Genetic Reference Panelextreme QTL genome-wide association mappingRNA interference

Identifiers

PMID34074789
PMCPMC8201854
OpenAlexW3165836234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.