Evidence map›Paper›PMID 34074773›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Iron robbery by intracellular pathogen via bacterial effector-induced ferritinophagy.

Qi Yan, Wenqing Zhang, Mingqun Lin, Omid Teymournejad, Khemraj Budachetri, Jeffrey Lakritz, Yasuko Rikihisa

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 50 citations in OpenAlex.

  1. mBio · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Antioxidants (Basel, Switzerland) · 2024
    Article
  11. International journal of molecular sciences · 2024
    Article
  12. mSphere · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. bioRxiv : the preprint server for biology · 2023
    Article
  18. Article
  19. Review
  20. Metagenome diversity illuminates origins of pathogen effectors.bioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qi YanDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.ORCID 0000-0002-5963-9242
Wenqing ZhangDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.ORCID 0000-0002-2250-4598
Mingqun LinDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.ORCID 0000-0002-9964-5460
Omid TeymournejadDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.ORCID 0000-0001-8448-7896
Khemraj BudachetriDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.ORCID 0000-0003-1254-792X
Jeffrey LakritzDepartment of Veterinary Preventive Medicine, The Ohio State University, Columbus, OH 43210.ORCID 0000-0003-2143-0416
Yasuko RikihisaDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210; rikihisa.1@osu.edu.ORCID 0000-0002-1870-5338
The Ohio State University · US

Funding

Keys to prevent iron hijacking and infection by intracellular bacteriaR01AI151065 · NIAID · OHIO STATE UNIVERSITY · PI RIKIHISA, YASUKO · 2020 to 2024
$1.9M
NIAID NIH HHS R01 AI151065
6 · The paper itself

Abstract

Iron is essential for survival and proliferation of

Indexed as

AutophagosomesAutophagyBacteriaBacterial ProteinsEhrlichia chaffeensisEhrlichiosisFerritinsGene Expression Regulation, BacterialHEK293 CellsHost-Pathogen InteractionsHumansIronMitochondriaMonocytesNuclear Receptor CoactivatorsReactive Oxygen SpeciesBacterial ProteinsFerritinsIronNCOA4 protein, humanNuclear Receptor CoactivatorsReactive Oxygen SpeciesRNA, Ribosomal, 16SType IV Secretion SystemsEhrlichia chaffeensisEtf-3ferritinophagyironT4SS effector

Identifiers

PMID34074773
PMCPMC8201858
OpenAlexW3165338802

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.