SynthesisBMC pediatrics2021
Prevalence and risk factors for antibiotic utilization in Chinese children.
Synthesis in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 24 citations in OpenAlex.
- Managing uncertainty in antibiotic decisions: factors influencing antibiotic use among chinese parents of children in a multi-source information environment.International journal of qualitative studies on health and well-being · 2026Article
- Determinants of antibiotic prescription pattern and appropriateness in paediatric care in Ghana: a generalized estimating equation approach.BMJ paediatrics open · 2026Article
- Predictors of Resistance in PediatricPathogens (Basel, Switzerland) · 2026Article
- Determinants of expert-advised antibiotic indication in pediatric emergency department, data from a cross-sectional prevalence survey.BMC pediatrics · 2026Article
- Extensive antibiotic use during early life and risk of frailty: a population-based cohort study in the UK biobank.BMC public health · 2026Article
- Antimicrobial prescribing patterns among pediatric outpatient encounters in primary healthcare centers in Bujumbura Mairie, Burundi.BMC primary care · 2025Article
- Long-Term or Recurrent Antibiotic Use in Early Life and the Risk of Type 2 Diabetes: A Population-Based Prospective Cohort and a Case-Control Study.Journal of diabetes · 2025Article
- Status and implications of the knowledge, attitudes and practices towards AWaRe antibiotic use, resistance and stewardship among low- and middle-income countries.JAC-antimicrobial resistance · 2025Review
- A Behavioral Analysis of Factors That Influence Antibiotic Prescribing in Hospitals: A Metasynthesis of Reviews.Open forum infectious diseases · 2025Review
- Prevalence of inappropriate use behaviors of antibiotics and related factors among parents in eastern China: an online cross-sectional survey.Frontiers in public health · 2025Article
- Clinical application of Myxovirus resistance protein A as a diagnostic biomarker to differentiate viral and bacterial respiratory infections in pediatric patients.Frontiers in immunology · 2025Article
- Prevalence and related factors for neck pain in military personnel: a systematic review.EFORT open reviews · 2024Article
- Antibiotic Use in Korean Children Diagnosed With Acute Bronchiolitis: Analysis of the National Health Insurance Reimbursement Data.Journal of Korean medical science · 2024Article
- Traditional Chinese medicine strategies to optimize antibiotic use and reduce the burden of antibiotic resistance in Chinese children.Frontiers in public health · 2024Article
- Article
- The Role of Uncertainty and Negative Emotion in Chinese Parents' Self-Medication of Children with Antibiotics.International journal of environmental research and public health · 2023Article
- Antibiotics administration without prescription in Bangladesh.IJID regions · 2023Article
- Weighing patient attributes in antibiotic prescribing for upper respiratory tract infections: A discrete choice experiment on primary care physicians in Hubei Province, China.Frontiers in public health · 2022Article
- Review
- Assessment of use of World Health Organization access, watch, reserve antibiotics and core prescribing indicators in pediatric outpatients in a tertiary care teaching hospital in Eastern India.Perspectives in clinical researchArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAntibiotic resistance poses a significant threat to public health globally. Irrational utilization of antibiotics being one of the main reasons of antibiotic resistant. Children as a special group, there's more chance of getting infected. Although most of the infection is viral in etiology, antibiotics still are the most frequently prescribed medications for children. Therefore, high use of antibiotics among children raises concern about the appropriateness of antibiotic prescribing. This systematic review aims to measuring prevalence and risk factors for antibiotic utilization in children in China.
methodsEnglish and Chinese databases were searched to identify relevant studies evaluating the prevalence and risk factors for antibiotic utilization in Chinese children (0-18 years), which were published between 2010 and July 2020. A Meta-analysis of prevalence was performed using random effect model. The Agency for Healthcare Research and Quality (AHRQ) and modified Jadad score was used to assess risk of bias of studies. In addition, we explored the risk factors of antibiotic utilization in Chinese children using qualitative analysis.
resultsOf 10,075 studies identified, 98 eligible studies were included after excluded duplicated studies. A total of 79 studies reported prevalence and 42 studies reported risk factors for antibiotic utilization in children. The overall prevalence of antibiotic utilization among outpatients and inpatients were 63.8% (35 studies, 95% confidence interval (CI): 55.1-72.4%), and 81.3% (41 studies, 95% CI: 77.3-85.2%), respectively. In addition, the overall prevalence of caregiver's self-medicating of antibiotics for children at home was 37.8% (4 studies, 95% CI: 7.9-67.6%). The high prevalence of antibiotics was associated with multiple factors, while lacking of skills and knowledge in both physicians and caregivers was the most recognized risk factor, caregivers put pressure on physicians to get antibiotics and self-medicating with antibiotics at home for children also were the main factors attributed to this issue.
conclusionThe prevalence of antibiotic utilization in Chinese children is heavy both in hospitals and home. It is important for government to develop more effective strategies to improve the irrational use of antibiotic, especially in rural setting.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.