Evidence map›Paper›PMID 34074198›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

4-Arylthiosemicarbazide derivatives as a new class of tyrosinase inhibitors and anti-

Adrian Bekier, Lidia Węglińska, Agata Paneth, Piotr Paneth, Katarzyna Dzitko

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Transient Adaptation ofInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Adrian BekierDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.ORCID https://orcid.org/0000-0002-4980-1074
Lidia WęglińskaDepartment of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0003-3114-0623
Agata PanethDepartment of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.ORCID https://orcid.org/0000-0002-8198-7702
Piotr PanethInstitute of Applied Radiation Chemistry, Lodz University of Technology, Lodz, Poland.ORCID https://orcid.org/0000-0002-3091-8387
Katarzyna DzitkoDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, Lodz, Poland.ORCID https://orcid.org/0000-0002-3265-0409
Medical University of Lublin · PLUniversity of Łódź · PLLodz University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report herein anti-proliferation effects of 4-arylthiosemicarbazides, with a cyclopentane substitution at

Indexed as

Antiprotozoal AgentsDose-Response Relationship, DrugEnzyme InhibitorsMolecular StructureMonophenol MonooxygenaseParasitic Sensitivity TestsSemicarbazidesStructure-Activity RelationshipToxoplasmaAntiprotozoal AgentsEnzyme InhibitorsMonophenol MonooxygenaseSemicarbazidesthiosemicarbazideMolecular dockingSAR analysisthiosemicarbazidesToxoplasma gondiityrosinase

Identifiers

PMID34074198
PMCPMC8174488
OpenAlexW3165305330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.