Evidence map›Paper›PMID 34074138›Full record

ReviewAntioxidants & redox signaling2021

ERO1-PDI Redox Signaling in Health and Disease.

Vishwanath Jha, Tripti Kumari, Vijayprakash Manickam, Zahra Assar, Kirk L Olson, Jeong-Ki Min, Jaehyung Cho

Open access · greenAbstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 44 citations in OpenAlex.

  1. Systematic optimization ofEngineering microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Vishwanath JhaDivision of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Tripti KumariDivision of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Vijayprakash ManickamDivision of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Zahra AssarCayman Chemical Company, Inc., Ann Arbor, Michigan, USA.
Kirk L OlsonCayman Chemical Company, Inc., Ann Arbor, Michigan, USA.
Jeong-Ki MinBiotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.
Jaehyung ChoDivision of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-2404-3446
Washington University in St. Louis · USCayman Chemical (United States) · USKorea Research Institute of Bioscience and Biotechnology · KR

Funding

Thiol isomerases in neutrophil recruitment and thromboinflammatory diseaseR01HL130028 · NHLBI · WASHINGTON UNIVERSITY · PI CHO, JAEHYUNG · 2016 to 2024
$3.6M
Thiol isomerases and ERO1α in sickle cell vaso-occlusionR01HL148280 · NHLBI · WASHINGTON UNIVERSITY · PI CHO, JAEHYUNG · 2019 to 2022
$1.9M
Ero1α in platelet activity and thrombosisR01HL146559 · NHLBI · WASHINGTON UNIVERSITY · PI CHO, JAEHYUNG · 2020 to 2023
$1.7M
Role of intravascular ERO1@ in acute lung injuryR01HL153047 · NHLBI · WASHINGTON UNIVERSITY · PI CHO, JAEHYUNG · 2020 to 2023
$1.6M
Identification of an inhibitor of PDI-GPIbalpha signaling as a novel antithromboinflammatory agentR33HL154107 · NHLBI · WASHINGTON UNIVERSITY · PI CHO, JAEHYUNG · 2020 to 2021
$1.1M
NHLBI NIH HHS R01 HL130028NHLBI NIH HHS R01 HL146559NHLBI NIH HHS R01 HL148280NHLBI NIH HHS R01 HL153047NHLBI NIH HHS R33 HL154107
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCardiovascular DiseasesHumansMembrane GlycoproteinsMetabolic DiseasesNeurodegenerative DiseasesOxidoreductasesProtein Disulfide-IsomerasesSignal TransductionERO1A protein, humanMembrane GlycoproteinsOxidoreductasesProtein Disulfide-IsomerasesdiseaseERO1inhibitorsoxidative ER stressPDIunfolded protein response

Identifiers

PMID34074138
PMCPMC8817699
OpenAlexW3164266707

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.