Evidence map›Paper›PMID 34074038›Full record

ArticleInternational journal of molecular sciences2021

Enhanced Anti-Tumor Activity in Mice with Temozolomide-Resistant Human Glioblastoma Cell Line-Derived Xenograft Using SN-38-Incorporated Polymeric Microparticle.

Tao-Chieh Yang, Shih-Jung Liu, Wei-Lun Lo, Shu-Mei Chen, Ya-Ling Tang, Yuan-Yun Tseng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Tao-Chieh YangDepartment of Neurosurgery, School of Medicine, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.
Shih-Jung LiuDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0003-2083-4865
Wei-Lun LoDivision of Neurosurgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235041, Taiwan.
Shu-Mei ChenDepartment of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110301, Taiwan.
Ya-Ling TangDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, Taiwan.
Yuan-Yun TsengDivision of Neurosurgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, New Taipei City 235041, Taiwan.ORCID 0000-0003-4968-3298
Chang Gung University · TWTaipei Medical University-Shuang Ho Hospital · TWChung Shan Medical University Hospital · TWTaipei Medical University Hospital · TW

Funding

Ministry of Science and Technology, Taiwan 108-2314-B-038-060-MY2
6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) has remained one of the most lethal and

Indexed as

AnimalsAntineoplastic Combined Chemotherapy ProtocolsApoptosisBrain NeoplasmsCell Line, TumorCell ProliferationDrug Delivery SystemsDrug LiberationDrug Resistance, NeoplasmGlioblastomaHumansIrinotecanMiceMicroplasticsMicroscopy, Electron, ScanningPolylactic Acid-Polyglycolic Acid CopolymerIrinotecanMicroplasticsPolylactic Acid-Polyglycolic Acid CopolymerTemozolomideglioblastoma multiforme (GBM)interstitial chemotherapypoly[(d,l)-lactide-co-glycolide] (PLGA)SN-38temozolomide-resistance

Identifiers

PMID34074038
PMCPMC8197307
OpenAlexW3165776254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.