Evidence map›Paper›PMID 34073951›Full record

ArticleInternational journal of molecular sciences2021

Ancient Bacterial Class

Nomfundo Nzuza, Tiara Padayachee, Puleng Rosinah Syed, Justyna Dorota Kryś, Wanping Chen, Dominik Gront, David R Nelson, Khajamohiddin Syed

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Cytochromes P450 involved in bacterial RiPP biosyntheses.Journal of industrial microbiology & biotechnology · 2023
    Review
  3. Article
  4. Lifestyles Shape the Cytochrome P450 Repertoire of the Bacterial PhylumInternational journal of molecular sciences · 2022
    Article
  5. Contrasting Health Effects ofInternational journal of molecular sciences · 2022
    Article
  6. Article
  7. Diversification of Ferredoxins across Living Organisms.Current issues in molecular biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Nomfundo NzuzaDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.
Tiara PadayacheeDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.ORCID 0000-0001-6667-9982
Puleng Rosinah SyedDepartment of Pharmaceutical Chemistry, College of Health Sciences, University of KwaZulu-Natal, Durban 4000, South Africa.
Justyna Dorota KryśFaculty of Chemistry, Biological and Chemical Research Center, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID 0000-0002-5318-8831
Wanping ChenDepartment of Molecular Microbiology and Genetics, University of Göttingen, 37077 Göttingen, Germany.
Dominik GrontFaculty of Chemistry, Biological and Chemical Research Center, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.ORCID 0000-0002-2260-2083
David R NelsonDepartment of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0003-0583-5421
Khajamohiddin SyedDepartment of Biochemistry and Microbiology, Faculty of Science and Agriculture, University of Zululand, KwaDlangezwa 3886, South Africa.ORCID 0000-0002-1497-3570
University of Zululand · ZAUniversity of Warsaw · PLUniversity of Göttingen · DEUniversity of KwaZulu-Natal · ZAUniversity of Tennessee Health Science Center · US

Funding

National Research Foundation, South Africa 114159Polish National Science Centre (NCN) 2018/29/B/ST6/01989
6 · The paper itself

Abstract

Cytochrome P450 monooxygenases (CYPs/P450s), heme-thiolate proteins, are well-known players in the generation of chemicals valuable to humans and as a drug target against pathogens. Understanding the evolution of P450s in a bacterial population is gaining momentum. In this study, we report comprehensive analysis of P450s in the ancient group of the bacterial class

Indexed as

Multigene FamilyAlphaproteobacteriaBacillotaBiosynthetic PathwaysCholesterolCyanobacteriaCytochrome P-450 Enzyme SystemData MiningEvolution, MolecularGenome, BacterialMycobacterium tuberculosisPhylogenySecondary MetabolismStreptomycesCholesterolCytochrome P-450 Enzyme SystemAlphaproteobacteriaannotationbiosynthetic gene clusterscholesterol oxidationCYP125cytochrome P450 monooxygenasegenome data mining

Identifiers

PMID34073951
PMCPMC8197338
OpenAlexW3164982346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.