Evidence map›Paper›PMID 34073936›Full record

ArticleMolecules (Basel, Switzerland)2021

Scale-Up Preparation of Crocins I and II from

Shuguang Guan, Qiaoli Pu, Yinan Liu, Honghong Wu, Wenbo Yu, Zifeng Pi, Shu Liu, Fengrui Song, Jingya Li, De-An Guo

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuguang GuanCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.ORCID 0000-0001-9482-3339
Qiaoli PuCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
Yinan LiuShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Honghong WuUniversity of Chinese Academy of Sciences, Beijing 100049, China.
Wenbo YuCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
Zifeng PiChangchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Shu LiuChangchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Fengrui SongChangchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Jingya LiShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
De-An GuoCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.

Funding

National Natural Science Foundation of China 81530095, 81673591National Standardization of Traditional Chinese Medicine Project ZYBZH-K-LN-01
6 · The paper itself

Abstract

Crocins are highly valuable natural compounds for treating human disorders, and they are also high-end spices and colorants in the food industry. Due to the limitation of obtaining this type of highly polar compound, the commercial prices of crocins I and II are expensive. In this study, macroporous resin column chromatography combined with high-speed counter-current chromatography (HSCCC) was used to purify crocins I and II from natural sources. With only two chromatographic steps, both compounds were simultaneously isolated from the dry fruit of

Indexed as

ATP Citrate (pro-S)-LyaseCarotenoidsCountercurrent DistributionEnzyme InhibitorsGardeniaSpectrum AnalysisATP Citrate (pro-S)-LyaseCarotenoidscrocinEnzyme Inhibitorscrocinshigh-speed counter-current chromatographyinhibitory activity on ATP citrate lyasemacroporous resin column chromatographypreparation method

Identifiers

PMID34073936
PMCPMC8197369

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.