Evidence map›Paper›PMID 34073934›Full record

ArticleViruses2021

Identification of Novel Candidate CD8

Pradeep Darshana Pushpakumara, Deshan Madhusanka, Saubhagya Dhanasekara, Chandima Jeewandara, Graham S Ogg, Gathsaurie Neelika Malavige

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Pradeep Darshana PushpakumaraCentre for Dengue Research, Department of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Deshan MadhusankaCentre for Dengue Research, Department of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Saubhagya DhanasekaraCentre for Dengue Research, Department of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Chandima JeewandaraCentre for Dengue Research, Department of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Graham S OggMRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX1 4BH, UK.
Gathsaurie Neelika MalavigeCentre for Dengue Research, Department of Immunology and Molecular Medicine, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
University of Sri Jayewardenepura · LKMRC Weatherall Institute of Molecular Medicine · GBUniversity of Oxford · GB

Funding

Medical Research Council MC_PC_20002Medical Research Council MC_UU_00008/5
6 · The paper itself

Abstract

Cross-reactive T cell immunity to seasonal coronaviruses (HCoVs) may lead to immunopathology or protection during SARS-CoV2 infection. To understand the influence of cross-reactive T cell responses, we used IEDB (Immune epitope database) and NetMHCpan (ver. 4.1) to identify candidate CD8

Indexed as

SeasonsAllelesAmino Acid SequenceAntigens, ViralCD8-Positive T-LymphocytesCOVID-19Cross ReactionsEpitopes, T-LymphocyteHLA AntigensHumansSARS-CoV-2Spike Glycoprotein, CoronavirusAntigens, ViralEpitopes, T-LymphocyteHLA AntigensSpike Glycoprotein, CoronavirusCD8+ T cell epitopesHKU-1HLA allelesNL-63OC-43SARS-CoV2seasonal coronaviruses

Identifiers

PMID34073934
PMCPMC8225204
OpenAlexW3132995409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.