Evidence map›Paper›PMID 34073891›Full record

ArticleCancers2021

Anxiety during Radiation Therapy: A Prospective Randomized Controlled Trial Evaluating a Specific One-on-One Procedure Announcement Provided by a Radiation Therapist.

Delphine Antoni, Céline Vigneron, Jean-Baptiste Clavier, Sébastien Guihard, Michel Velten, Georges Noel

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. A machine learning approach to profiling anxiety risk among cancer patients on treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Association of Breast Cancer Patient Education with Disease Understanding and Anxiety: Analysis Using the EORTC QLQ-INFO25 and HADS.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Delphine AntoniDepartment of Radiotherapy, ICANS, Institut de Cancérologie Strasbourg Europe, Paul Strauss Comprehensive Cancer Center, 17 rue Albert Calmette, 67200 Strasbourg, France.
Céline VigneronDepartment of Radiotherapy, ICANS, Institut de Cancérologie Strasbourg Europe, Paul Strauss Comprehensive Cancer Center, 17 rue Albert Calmette, 67200 Strasbourg, France.
Jean-Baptiste ClavierDepartment of Radiotherapy, ICANS, Institut de Cancérologie Strasbourg Europe, Paul Strauss Comprehensive Cancer Center, 17 rue Albert Calmette, 67200 Strasbourg, France.
Sébastien GuihardDepartment of Radiotherapy, ICANS, Institut de Cancérologie Strasbourg Europe, Paul Strauss Comprehensive Cancer Center, 17 rue Albert Calmette, 67200 Strasbourg, France.
Michel VeltenClinical Research Department, Institut de Cancérologie Strasbourg Europe, 17 rue Albert Calmette, 67200 Strasbourg, France.
Georges NoelDepartment of Radiotherapy, ICANS, Institut de Cancérologie Strasbourg Europe, Paul Strauss Comprehensive Cancer Center, 17 rue Albert Calmette, 67200 Strasbourg, France.
Institut de Cancérologie Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnxiety impacts patient outcomes and quality of life in response to cancer diagnosis. A prospective phase 3 trial randomizing 126 patients was conducted to determine whether a specific one-on-one procedure announcement provided by a radiation therapist before CT scan simulation decreases anxiety for patients with breast cancer requiring radiotherapy. MATERIAL AND

methodsAnxiety was measured using the STAI form, and the QLQ-C30 and BR-23 questionnaires were used to evaluate quality of life.

resultsMean trait or state anxiety scores before CT scan simulation, before the first and second sessions, and at the end of radiation treatment were not significantly different. We observed a decrease in the level of anxiety with time; however, no significant difference in mean state anxiety scores at any of the time intervals was detected. Factors, such as anxiety trait score, professional and marital status, age, and use of alternative therapy, did not significantly influence the evolution of anxiety status over time or the mean value. Anxiety was significantly influenced by the level of fatigue. Patients who benefited from the radiation therapists' advice felt significantly better informed.

conclusionsThe one-on-one program announcement occurring before CT scan simulation led to patients being more informed and greater satisfaction but did not decrease anxiety.

Indexed as

anxietybreast cancerone-on-one announcementradiation therapist

Identifiers

PMID34073891
PMCPMC8197250
OpenAlexW3164881421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.