Evidence map›Paper›PMID 34073866›Full record

ArticleLife (Basel, Switzerland)2021

Inappropriateness of Antibiotic Prescribing in Medical, Surgical and Intensive Care Units: Results of a Multicentre Observational Study.

Margherita Macera, Federica Calò, Lorenzo Onorato, Giovanni Di Caprio, Caterina Monari, Antonio Russo, Anna Galdieri, Antonio Giordano, Patrizia Cuccaro, Nicola Coppola

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Margherita MaceraDepartment of Mental Health and Public Medicine. University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Federica CalòDepartment of Mental Health and Public Medicine. University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Lorenzo OnoratoDepartment of Mental Health and Public Medicine. University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Giovanni Di CaprioInfectious Diseases Unit, AORN Sant'Anna and San Sebastiano, Caserta Hospital, 81100 Caserta, Italy.
Caterina MonariDepartment of Mental Health and Public Medicine. University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.ORCID 0000-0003-2622-0573
Antonio RussoDepartment of Mental Health and Public Medicine. University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.ORCID 0000-0002-4224-5343
Anna GaldieriDirezione Sanitaria, AOU Vanvitell, University of Campania, 80138 Naples, Italy.
Antonio GiordanoDirezione Generale, AOU Vanvitell, University of Campania, 80138 Naples, Italy.
Patrizia CuccaroDirezione Sanitaria, AORN Sant'Anna and San Sebastiano, Caserta Hospital, 81100 Caserta, Italy.
Nicola CoppolaDepartment of Mental Health and Public Medicine. University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.ORCID 0000-0001-5897-4949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objectives of the present study were to provide a snapshot analysis of antibiotic appropriateness in two hospitals in Southern Italy in three specific areas, surgical, medical and intensive care, and to evaluate the risk factors associated with inappropriateness in antimicrobial prescriptions. We conducted a multicentre observational study in two hospitals in the Campania region. We collected data of all patients admitted on the day of evaluation to antibiotic therapy or prophylaxis through a case report form. The primary outcome was to assess the inappropriateness of antibiotic prescribing, related to the spectrum, dose, route of administration and duration of treatment-in particular, to assess whether there was a difference in the adequacy of the prescriptive practice in the medical, surgical and intensive sectors. Prescriptive inappropriateness was more frequently observed in surgical units (79.8% of the 104 antimicrobial prescriptions) than in medical units (53.8% of the 65 prescriptions,

Indexed as

antibiotic appropriatenessantibiotic prescriptionantimicrobial resistance

Identifiers

PMID34073866
PMCPMC8225033

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.