ReviewLife (Basel, Switzerland)2021
Current Perspectives on Idiopathic Intracranial Hypertension without Papilloedema.
Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Identifying MicroRNA Biomarkers in Idiopathic Intracranial Hypertension: A Pilot Study.Neurology · 2026Trial
- Idiopathic Intracranial Hypertension with and Without Papilledema: A Comparative Cohort Study.Brain sciences · 2026Article
- Magnetic Resonance Imaging Findings in Children with Papilledema.Neuro-ophthalmology (Aeolus Press) · 2026Article
- Article
- Idiopathic Intracranial Hypertension in Neonates, Infants, and Toddlers.Journal of clinical medicine · 2025Review
- Article
- Diagnostic process, misdiagnosis and bias in suspected idiopathic intracranial hypertension: a retrospective observational cohort study.BMJ neurology open · 2025Article
- An interdisciplinary integrated specialized one-stop outpatient clinic for idiopathic intracranial hypertension-a comprehensive assessment of clinical outcome.European journal of neurology · 2024Article
- Idiopathic intracranial hypertension in Asians: a retrospective dual-center study.The journal of headache and pain · 2024Article
- Progress and recognition of idiopathic intracranial hypertension: A narrative review.CNS neuroscience & therapeutics · 2024Review
- Imaging the brain: diagnosis aided by structural features on neuroimaging studies.Eye (London, England) · 2024Review
- Managing idiopathic intracranial hypertension in the eye clinic.Eye (London, England) · 2024Review
- Optic Nerve Head and Retinal Changes in Idiopathic Intracranial Hypertension: Correlation with Short-Term Cerebrospinal Fluid Pressure Monitoring.Journal of clinical medicine · 2024Article
- Does a Healthy Weight Body Mass Index at Onset of Idiopathic Intracranial Hypertension Change the Outcomes? A United Kingdom Prospective Cohort Study.Neuro-ophthalmology (Aeolus Press) · 2024Article
- Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms.Nature reviews. Neurology · 2023Review
- Overlap and Differences in Migraine and Idiopathic Intracranial Hypertension.Current pain and headache reports · 2023Review
- Inaccuracy of idiopathic intracranial hypertension diagnosis in case reports.Eye (London, England) · 2023Review
- A Neuro-Ophthalmologist's Guide to Advances in Intracranial Pressure Measurements.Eye and brain · 2023Review
- Transverse Sinus Stenting Reverses Medically Refractory Idiopathic Intracranial Hypertension.Frontiers in ophthalmology · 2022Article
- Evolving Evidence in Idiopathic Intracranial Hypertension.Life (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pseudotumor cerebri syndrome embraces disorders characterised by raised intracranial pressure, where the commonest symptom is headache (90%). Idiopathic intracranial hypertension without papilloedema (IIHWOP) is increasingly recognised as a source of refractory headache symptoms and resultant neurological disability. Although the majority of patients with IIHWOP are phenotypically similar to those with idiopathic intracranial hypertension (IIH), it remains uncertain as to whether IIHWOP is nosologically distinct from IIH. The incidence, prevalence, and the degree of association with the world-wide obesity epidemic is unknown. Establishing a diagnosis of IIHWOP can be challenging, as often lumbar puncture is not routinely part of the work-up for refractory headaches. There are published diagnostic criteria for IIHWOP; however, some report uncertainty regarding a pathologically acceptable cut off for a raised lumbar puncture opening pressure, which is a key criterion. The literature provides little information to help guide clinicians in managing patients with IIHWOP. Further research is therefore needed to better understand the mechanisms that drive the development of chronic daily headaches and a relationship to intracranial pressure; and indeed, whether such patients would benefit from therapies to lower intracranial pressure. The aim of this narrative review was to perform a detailed search of the scientific literature and provide a summary of historic and current opinion regarding IIHWOP.
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