Evidence map›Paper›PMID 34073838›Full record

ArticleNutrients2021

Hepatic

Han Fang, Kirsten P Stone, Sujoy Ghosh, Laura A Forney, Landon C Sims, LeighAnn Vincik, Thomas W Gettys

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Han FangLaboratory of Nutrient Sensing & Adipocyte Signaling, 6400 Perkins Road, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.ORCID 0000-0002-0450-5087
Kirsten P StoneLaboratory of Nutrient Sensing & Adipocyte Signaling, 6400 Perkins Road, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.ORCID 0000-0001-5511-1638
Sujoy GhoshLaboratory of Computational Biology, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Laura A ForneyDepartment of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, 7000 Fannin St, Houston, TX 77030, USA.
Landon C SimsLaboratory of Nutrient Sensing & Adipocyte Signaling, 6400 Perkins Road, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
LeighAnn VincikLaboratory of Nutrient Sensing & Adipocyte Signaling, 6400 Perkins Road, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.
Thomas W GettysLaboratory of Nutrient Sensing & Adipocyte Signaling, 6400 Perkins Road, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA.ORCID 0000-0001-7125-7995
Pennington Biomedical Research Center · USThe University of Texas Health Science Center at Houston · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
Transgenics CoreP30GM118430 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2016 to 2020
$5.8M
MECHANISMS OF METABOLIC REGULATION BY DIETARY METHIONINE RESTRICTIONR01DK096311 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2012 to 2020
$2.7M
Sable Systems Promethion for Mouse Metabolic AnalysisS10OD023703 · OD · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI MORRISON, CHRISTOPHER D · 2017 to 2017
$626k
National Health and Medical Research Council WBS R913200076263NIDDK NIH HHS R01 DK096311NIGMS NIH HHS P30 GM118430NIGMS NIH HHS U54 GM104940NIH HHS 2P30 DK072476NIH HHS DK-096311NIH HHS P20-GM103528NIH HHS S10 OD023703NIH HHS U54 GM104940
6 · The paper itself

Abstract

The principal sensing of dietary methionine restriction (MR) occurs in the liver, where it activates multiple transcriptional programs that mediate various biological components of the response. Hepatic

Indexed as

AdiposityAnimalsBody WeightEnergy MetabolismFibroblast Growth FactorsGenotypeLiverMaleMethionineMiceMice, Inbred C57BLNF-E2-Related Factor 2ObesityPhenotypefibroblast growth factor 21Fibroblast Growth FactorsMethionineNF-E2-Related Factor 2essential amino acidFGF21integrated stress responseNfe2l2nutrient sensingobesity

Identifiers

PMID34073838
PMCPMC8225036
OpenAlexW3165398441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.