Evidence map›Paper›PMID 34073827›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

A Case of Pathological Complete Response and Resolution of Dermatomyositis Following Neoadjuvant Chemotherapy in HER2-Positive Early Breast Cancer.

Marta Piras, Martina Panebianco, Matteo Garibaldi, Michela Roberto, Gioia Merlonghi, Patrizia Pellegrini, Paolo Marchetti

Open access · goldAbstract readCase Reports
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marta PirasOncology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", 00189 Rome, Italy.
Martina PanebiancoOncology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", 00189 Rome, Italy.
Matteo GaribaldiNeuromuscular and Rare Disease Centre, Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), SAPIENZA University of Rome, Sant'Andrea Hospital, 00189 Rome, Italy.ORCID 0000-0003-1830-2886
Michela RobertoOncology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", 00189 Rome, Italy.ORCID 0000-0001-5339-8348
Gioia MerlonghiNeuromuscular and Rare Disease Centre, Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), SAPIENZA University of Rome, Sant'Andrea Hospital, 00189 Rome, Italy.
Patrizia PellegriniOncology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", 00189 Rome, Italy.
Paolo MarchettiOncology Unit, Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, University "La Sapienza", 00189 Rome, Italy.ORCID 0000-0002-9064-8761
Azienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDermatomyositis (DM) is an idiopathic inflammatory myopathy (IIM) mainly characterized by subacute muscle weakness and skin rash sometimes associated with malignancy. CASE PRESENTATION: A 61-year-old female was admitted to our hospital because of progressive proximal muscular weakness, heliotropic rash and left breast rash. Muscle biopsy findings were consistent with dermatomyositis (DM). A full panel of myositis associated (MAA) and specific antibodies (MSA) revealed the presence of anti-nuclear antibodies (1:160, speckled), Anti-Ro52 and anti TIF1-γ antibodies. A whole body Computed Tomography Scan showed three left mammary nodules and homolateral axillary lymphadenopathy. The breast biopsy confirmed the diagnosis of ductal carcinoma. Patient was initiated to neoadjuvant chemotherapy followed by surgery for cancer, and corticosteroid and intravenous immunoglobulins for DM with a complete resolution of muscle weakness and pathological complete response of breast cancer.

Indexed as

Breast NeoplasmsCarcinoma, Ductal, BreastDermatomyositisMyositisFemaleHumansMiddle AgedNeoadjuvant Therapybreast cancerdermatomyositisneoadjuvant chemotherapyparaneoplastictrastuzumab

Identifiers

PMID34073827
PMCPMC8161769
OpenAlexW3165108444

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.