Evidence map›Paper›PMID 34073781›Full record

ArticleMolecules (Basel, Switzerland)2021

β-Sitosterol-D-Glucopyranoside Mimics Estrogenic Properties and Stimulates Glucose Utilization in Skeletal Muscle Cells.

Jyotsana Pandey, Kapil Dev, Sourav Chattopadhyay, Sleman Kadan, Tanuj Sharma, Rakesh Maurya, Sabyasachi Sanyal, Mohammad Imran Siddiqi, Hilal Zaid, Akhilesh Kumar Tamrakar

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Aspects of β-sitosterol's Pharmacology, Nutrition and Analysis.Current pharmaceutical biotechnology · 2025
    Review
  2. Review
  3. Review
  4. PhytoestrogenVaccines · 2023
    Article
  5. Tinosporaside fromMolecules (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Antioxidants (Basel, Switzerland) · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Jyotsana PandeyBiochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.ORCID 0000-0002-0606-6903
Kapil DevMedicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Sourav ChattopadhyayBiochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Sleman KadanQasemi Research Center, Al-Qasemi Academic College, P.O. Box 124, Baqa El-Gharbia 30100, Israel.
Tanuj SharmaMolecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Rakesh MauryaMedicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Sabyasachi SanyalBiochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Mohammad Imran SiddiqiMolecular and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.ORCID 0000-0001-5655-5484
Hilal ZaidQasemi Research Center, Al-Qasemi Academic College, P.O. Box 124, Baqa El-Gharbia 30100, Israel.
Akhilesh Kumar TamrakarBiochemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Central Drug Research Institute · INAl-Qasemi Academic College of Education · IL

Funding

Council of Scientific and Industrial Research, India BSC0102
6 · The paper itself

Abstract

Estrogenic molecules have been reported to regulate glucose homeostasis and may be beneficial for diabetes management. Here, we investigated the estrogenic effect of

Indexed as

Molecular MimicryGlucoseGlucose Transporter Type 4HEK293 CellsHumansMagnetic Resonance SpectroscopyMass SpectrometryMCF-7 CellsMuscle, SkeletalPhosphatidylinositol 3-KinasesPhytoestrogensProto-Oncogene Proteins c-aktSignal TransductionSitosterolsgamma-sitosterolGlucoseGlucose Transporter Type 4Phosphatidylinositol 3-KinasesPhytoestrogensProto-Oncogene Proteins c-aktSitosterolsSLC2A4 protein, humanCupressus sempervirensglucose uptakeinsulin resistancephytoestrogenskeletal muscle

Identifiers

PMID34073781
PMCPMC8197182
OpenAlexW3165207916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.