Evidence map›Paper›PMID 34073649›Full record

ReviewLife (Basel, Switzerland)2021

Personalized Nutrition Approach in Pregnancy and Early Life to Tackle Childhood and Adult Non-Communicable Diseases.

Shaikha Alabduljabbar, Sara Al Zaidan, Arun Prasath Lakshmanan, Annalisa Terranegra

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

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  17. Epigenetics of pregnancy: looking beyond the DNA code.Journal of assisted reproduction and genetics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shaikha AlabduljabbarMother and Child Health Program, Research Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.ORCID 0000-0002-2072-2188
Sara Al ZaidanMother and Child Health Program, Research Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.
Arun Prasath LakshmananMother and Child Health Program, Research Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.ORCID 0000-0001-9738-7667
Annalisa TerranegraMother and Child Health Program, Research Department, Sidra Medicine, P.O. Box 26999, Doha, Qatar.ORCID 0000-0001-9274-5373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of childhood and adult non-communicable diseases (NCD) is associated with environmental factors, starting from intrauterine life. A new theory finds the roots of epigenetic programming in parental gametogenesis, continuing during embryo development, fetal life, and finally in post-natal life. Maternal health status and poor nutrition are widely recognized as implications in the onset of childhood and adult diseases. Early nutrition, particularly breastfeeding, also plays a primary role in affecting the health status of an individual later in life. A poor maternal diet during pregnancy and lack of breastfeeding can cause a nutrient deficiency that affects the gut microbiota, and acts as a cofactor for many pathways, impacting the epigenetic controls and transcription of genes involved in the metabolism, angiogenesis, and other pathways, leading to NCDs in adult life. Both maternal and fetal genetic backgrounds also affect nutrient adsorption and functioning at the cellular level. This review discusses the most recent evidence on maternal nutrition and breastfeeding in the development of NCD, the potentiality of the omics technologies in uncovering the molecular mechanisms underlying it, with the future prospective of applying a personalized nutrition approach to prevent and treat NCD from the beginning of fetal life.

Indexed as

breastfeedingepigeneticsgut microbiotanon-communicable diseasesnutrigeneticsprecision nutritionpregnancytranscriptomics

Identifiers

PMID34073649
PMCPMC8224671
OpenAlexW3165223855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.