Evidence map›Paper›PMID 34073604›Full record

ArticleInternational journal of molecular sciences2021

Phenolic Profiles of Red Wine Relate to Vascular Endothelial Benefits Mediated by SIRT1 and SIRT6.

Nunzia D'Onofrio, Elisa Martino, Giuseppina Chianese, Francesca Coppola, Luigi Picariello, Luigi Moio, Maria Luisa Balestrieri, Angelita Gambuti, Martino Forino

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nunzia D'OnofrioDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.
Elisa MartinoDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.
Giuseppina ChianeseDepartment of Pharmacy, University of Naples Federico II, Via D. Montesano, 49, 80131 Naples, Italy.ORCID 0000-0002-1008-3167
Francesca CoppolaDepartment of Agricultural Sciences, Section of Vine and Wine Sciences, University of Naples Federico II, Viale Italia, 83100 Avellino, Italy.ORCID 0000-0002-1620-6818
Luigi PicarielloDepartment of Agricultural Sciences, Section of Vine and Wine Sciences, University of Naples Federico II, Viale Italia, 83100 Avellino, Italy.ORCID 0000-0003-1828-2248
Luigi MoioDepartment of Agricultural Sciences, Section of Vine and Wine Sciences, University of Naples Federico II, Viale Italia, 83100 Avellino, Italy.
Maria Luisa BalestrieriDepartment of Precision Medicine, University of Campania Luigi Vanvitelli, Via L. De Crecchio 7, 80138 Naples, Italy.ORCID 0000-0001-6001-1789
Angelita GambutiDepartment of Agricultural Sciences, Section of Vine and Wine Sciences, University of Naples Federico II, Viale Italia, 83100 Avellino, Italy.ORCID 0000-0001-9245-6635
Martino ForinoDepartment of Agricultural Sciences, Section of Vine and Wine Sciences, University of Naples Federico II, Viale Italia, 83100 Avellino, Italy.ORCID 0000-0001-8036-3546
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

PON I&C 2014-2020 CAPSULE - F/200016/01-03/X45.Università degli Studi della Campania Luigi Vanvitelli Valere 2019
6 · The paper itself

Abstract

Dietary phenolic compounds possess potent bioactivity against inflammatory pathways of chronic inflammatory conditions, such as type 2 diabetes. Here, the phenolic profile and bioactivity of Italian red wines Gaglioppo, Magliocco, and Nerello Mascalese were characterized. NMR, HPLC/UV-Vis and spectrophotometric characterization showed that Magliocco was the richest wine in monomeric anthocyanins (two-fold), catechins, and low molecular weight phenolics (LMWP). A positive correlation was observed between the polyphenolic content and antioxidant capacity (

Indexed as

WineAntioxidantsCell LineEndothelial CellsHumansPhenolsSirtuin 1SirtuinsAntioxidantsPhenolsSIRT1 protein, humanSIRT6 protein, humanSirtuin 1Sirtuinsantioxidanthyperglycemiainsulin resistancepolyphenolsred winessirtuins

Identifiers

PMID34073604
PMCPMC8198779
OpenAlexW3164591596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.