Evidence map›Paper›PMID 34073577›Full record

ArticleViruses2021

Kinetics of Neutralizing Antibodies of COVID-19 Patients Tested Using Clinical D614G, B.1.1.7, and B 1.351 Isolates in Microneutralization Assays.

Jenni Virtanen, Ruut Uusitalo, Essi M Korhonen, Kirsi Aaltonen, Teemu Smura, Suvi Kuivanen, Sari H Pakkanen, Sointu Mero, Anu Patjas, Marianna Riekkinen and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  8. Neutralising capacity against Delta (B.1.617.2) and other variants of concern following Comirnaty (BNT162b2, BioNTech/Pfizer) vaccination in health care workers, Israel.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 2 countries.

Jenni VirtanenDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Ruut UusitaloDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0003-4170-8809
Essi M KorhonenDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0003-4730-7715
Kirsi AaltonenDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Teemu SmuraDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Suvi KuivanenDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
Sari H PakkanenHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Sointu MeroHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-3625-6273
Anu PatjasHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Marianna RiekkinenHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.
Anu KanteleHuman Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland.ORCID 0000-0002-0004-1000
Visa NurmiDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0001-8052-5592
Klaus HedmanDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0003-1779-7960
Jussi HepojokiDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0001-5699-214X
Tarja SironenDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0002-2344-2755
Eili HuhtamoDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0001-9640-6547
Olli VapalahtiDepartment of Virology, Faculty of Medicine, University of Helsinki, 00290 Helsinki, Finland.
University of Helsinki · FI

Funding

Academy of FinlandHelsingin ja Uudenmaan Sairaanhoitopiiri TYH2018322Horizon 2020 VEO 874735Jane ja Aatos Erkon Säätiö
6 · The paper itself

Abstract

Increasing evidence suggests that some newly emerged SARS-CoV-2 variants of concern (VoCs) resist neutralization by antibodies elicited by the early-pandemic wild-type virus. We applied neutralization tests to paired recoveree sera (

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralChlorocebus aethiopsCoronavirus Nucleocapsid ProteinsCOVID-19HumansImmunoglobulin GKineticsNeutralization TestsPhosphoproteinsSARS-CoV-2Severity of Illness IndexSpike Glycoprotein, CoronavirusVero CellsAntibodies, NeutralizingAntibodies, ViralCoronavirus Nucleocapsid ProteinsImmunoglobulin Gnucleocapsid phosphoprotein, SARS-CoV-2PhosphoproteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2immunityneutralizing antibodiesSARS-CoV-2

Identifiers

PMID34073577
PMCPMC8229637
OpenAlexW3165724335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.