Evidence map›Paper›PMID 34073539›Full record

ReviewJournal of clinical medicine2021

Diagnosis, Investigation and Management of Patients with Acute and Chronic Myocardial Injury.

Caelan Taggart, Ryan Wereski, Nicholas L Mills, Andrew R Chapman

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Key Characteristics of Cardiovascular Toxicants.Environmental health perspectives · 2021
    Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Caelan TaggartBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4SA, UK.ORCID 0000-0001-7379-5439
Ryan WereskiBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4SA, UK.ORCID 0000-0001-6485-453X
Nicholas L MillsBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4SA, UK.ORCID 0000-0003-0533-7991
Andrew R ChapmanBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4SA, UK.
University of Edinburgh · GB

Funding

British Heart Foundation CH/F/21/90010Medical Research Council MR/V007017/1
6 · The paper itself

Abstract

The application of high-sensitivity cardiac troponins in clinical practice has led to an increase in the recognition of elevated concentrations in patients without myocardial ischaemia. The Fourth Universal Definition of Myocardial Infarction encourages clinicians to classify such patients as having an acute or chronic myocardial injury based on the presence or absence of a rise or a fall in cardiac troponin concentrations. Both conditions may be caused by a variety of cardiac and non-cardiac conditions, and evidence suggests that clinical outcomes are worse than patients with myocardial infarction due to atherosclerotic plaque rupture, with as few as one-third of patients alive at 5 years. Major adverse cardiovascular events are comparable between populations, and up to three-fold higher than healthy individuals. Despite this, no evidence-based strategies exist to guide clinicians in the investigation of non-ischaemic myocardial injury. This review explores the aetiology of myocardial injury and proposes a simple framework to guide clinicians in early assessment to identify those who may benefit from further investigation and treatment for those with cardiovascular disease.

Indexed as

myocardial infarctionmyocardial injuryuniversal definition

Identifiers

PMID34073539
PMCPMC8199345
OpenAlexW3164186707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.