Evidence map›Paper›PMID 34073458›Full record

ArticleInternational journal of molecular sciences2021

Treg-Resistant Cytotoxic CD4

Cindy Hoeks, Marjan Vanheusden, Liesbet M Peeters, Piet Stinissen, Bieke Broux, Niels Hellings

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Cytomegalovirus Drives the Development of Cytotoxic CD4Neurology(R) neuroimmunology & neuroinflammation · 2026
    Article
  2. Cytotoxic CD4Signal transduction and targeted therapy · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cindy HoeksNeuro Immune Connections & Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Marjan VanheusdenNeuro Immune Connections & Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Liesbet M PeetersNeuro Immune Connections & Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Piet StinissenNeuro Immune Connections & Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Bieke BrouxNeuro Immune Connections & Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.ORCID 0000-0001-8509-2415
Niels HellingsNeuro Immune Connections & Repair Lab, Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Martelarenlaan 42, 3500 Hasselt, Belgium.
Hasselt University · BE

Funding

CSRD VA 1
6 · The paper itself

Abstract

Cytotoxic CD4

Indexed as

Cell ProliferationAdultAutoimmune DiseasesCTLA-4 AntigenFemaleGranzymesHumansInterleukin-10MaleMiddle AgedProgrammed Cell Death 1 ReceptorTh17 CellsT-Lymphocytes, RegulatoryCTLA-4 AntigenCTLA4 protein, humanGranzymesGZMB protein, humanIL10 protein, humanInterleukin-10PDCD1 protein, humanProgrammed Cell Death 1 ReceptorautoimmunityCD4 CTLcytotoxic CD4 T cellsproliferationregulatory CD4 T cellssuppression

Identifiers

PMID34073458
PMCPMC8198086
OpenAlexW3165630980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.