Evidence map›Paper›PMID 34073441›Full record

ArticleAnimals : an open access journal from MDPI2021

Seo Woo Kim, Jeong Hyo Lee, Ji Seon Han, Seung Pyo Shin, Tae Sub Park

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Seo Woo KimGraduate School of International Agricultural Technology, Seoul National University, Pyeongchang-gun 25354, Gangwon-do, Korea.
Jeong Hyo LeeInstitute of Green-Bio Science and Technology, Seoul National University, Pyeongchang-gun 25354, Gangwon-do, Korea.
Ji Seon HanGraduate School of International Agricultural Technology, Seoul National University, Pyeongchang-gun 25354, Gangwon-do, Korea.
Seung Pyo ShinInstitute of Green-Bio Science and Technology, Seoul National University, Pyeongchang-gun 25354, Gangwon-do, Korea.
Tae Sub ParkGraduate School of International Agricultural Technology, Seoul National University, Pyeongchang-gun 25354, Gangwon-do, Korea.ORCID 0000-0002-0372-5467
Seoul National University · KR

Funding

Cooperative Research Program for Agriculture Science & Technology Development, Rural Development Administration, Korea PJ01621901National Research Foundation of Korea NRF-2021R1A2C1012056
6 · The paper itself

Abstract

A bioreactor can be used for mass production of therapeutic proteins and other bioactive substances. Although various methods have been developed using microorganisms and animal cells, advanced strategies are needed for the efficient production of biofunctional proteins. In microorganisms, post-translational glycosylation and modification are not performed properly, while animal cell systems require more time and expense. To overcome these problems, new methods using products from transgenic animals have been considered, such as genetically modified cow's milk and hen's eggs. In this study, based on a non-viral

Indexed as

bioreactorhuman cystatin CpiggyBac transposontransgenic chickens

Identifiers

PMID34073441
PMCPMC8226945
OpenAlexW3164348494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.