Evidence map›Paper›PMID 34073390›Full record

ArticleInternational journal of molecular sciences2021

Seounghun Lee, Hyo-Jung Shin, Chan Noh, Song-I Kim, Young-Kwon Ko, Sun-Yeul Lee, Chaeseong Lim, Boohwi Hong, Sin-Young Yang, Dong-Woon Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
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  9. Article
  10. Rejuvenating aged microglia by p16Molecular neurodegeneration · 2024
    Article
  11. Article
  12. Review
  13. DNA Methylation and Non-Coding RNAs during Tissue-Injury Associated Pain.International journal of molecular sciences · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Seounghun LeeDepartment of Anesthesiology and Pain Medicine, Chungnam National University Sejong Hospital, 20 Bodeum 7-ro, Sejong 30099, Korea.ORCID 0000-0002-5355-028X
Hyo-Jung ShinDepartment of Anatomy and Cell Biology, Chungnam National University College of Medicine, Daejeon 35015, Korea.ORCID 0000-0002-3530-101X
Chan NohDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Song-I KimDepartment of Anatomy and Cell Biology, Chungnam National University College of Medicine, Daejeon 35015, Korea.
Young-Kwon KoDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Sun-Yeul LeeDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Chaeseong LimDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.ORCID 0000-0002-2356-8999
Boohwi HongDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.ORCID 0000-0003-2468-9271
Sin-Young YangDepartment of Anesthesiology and Pain Medicine, Daejeon Veterans Hospital, 147 Daechoong-ro 82, Daedeok-gu, Daejeon 34314, Korea.
Dong-Woon KimDepartment of Anatomy and Cell Biology, Chungnam National University College of Medicine, Daejeon 35015, Korea.ORCID 0000-0001-7691-1394
Won-Hyung LeeDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Yoon-Hee KimDepartment of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea.
Chungnam National University · KRVeterans Health Service Medical Center · KR

Funding

Chungnam National University Hospital Research Fund 2019-CF-024National Research Foundation of Korea NRF-2019R1A2C2004884National Research Foundation of Korea NRF-2020R1A2C1007575National Research Foundation of Korea NRF-2020R1C1C1005423National Research Foundation of Korea NRF-2020R1I1A1A0105309611
6 · The paper itself

Abstract

Activation of nuclear factor-kappa B (NF-κB) in microglia plays a decisive role in the progress of neuropathic pain, and the inhibitor of kappa B (IκB) is a protein that blocks the activation of NF-κB and is degraded by the inhibitor of NF-κB kinase subunit beta (IKBKB). The role of

Indexed as

AnimalsDrug CarriersI-kappa B KinaseMaleMicrogliaNanoparticlesNeuralgiaPolylactic Acid-Polyglycolic Acid CopolymerRatsRats, Sprague-DawleyRNA, Small InterferingDrug CarriersI-kappa B KinaseIkbkb protein, ratPolylactic Acid-Polyglycolic Acid CopolymerRNA, Small InterferingIKBKBmicroglianeuropathic painpoly (lactic-co-glycolic acid) nanoparticlesiRNA

Identifiers

PMID34073390
PMCPMC8203094
OpenAlexW3164849418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.