ArticleBrain sciences2021
Association of Severe Retinopathy of Prematurity and Bronchopulmonary Dysplasia with Adverse Neurodevelopmental Outcomes in Preterm Infants without Severe Brain Injury.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Identifying the risk factors of autism spectrum disorders in infants born preterm: a systematic review and meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Pooled it
- The Establishment of a Simplified Clinical Scoring System for Neurodevelopmental Follow-Up and Its Application in Very Preterm Infants.Child: care, health and development · 2026Article
- Lifelong cognitive and motor outcomes after being born small for gestational age or with fetal growth restriction.World journal of clinical pediatrics · 2026Review
- Article
- Adverse neurodevelopment after multiple sepsis and/or necrotizing enterocolitis in preterm infants: revisiting single-episode paradigm.Pediatric research · 2026Article
- Resolvin D1 improves bleomycin-induced alveolar maturation arrest in newborn rats.Scientific reports · 2025Article
- Association between the motor optimality score-revised and clinical variables of preterm infants.BMC pediatrics · 2025Article
- Are the Risk Factors for Bronchopulmonary Dysplasia and Retinopathy of Prematurity in Very Low-Birth-Weight Infants the Same?Children (Basel, Switzerland) · 2025Article
- IC100, a humanized therapeutic monoclonal anti-ASC antibody alleviates oxygen-induced retinopathy in mice.Angiogenesis · 2024Article
- Impact of bronchopulmonary dysplasia on brain GABA concentrations in preterm infants: Prospective cohort study.Early human development · 2023Article
- Association of Positive Bacterial Cultures Obtained from the Throat, Anus, Ear, Bronchi and Blood in Very-Low-Birth-Weight Premature Infants with Severe Retinopathy of Prematurity-Own Observations.Journal of clinical medicine · 2023Article
- Neurodevelopmental outcomes of preterm infants.Clinical and experimental pediatrics · 2023Article
- [Influence of bronchopulmonary dysplasia on cerebral blood flow in preterm infants: a prospective study based on arterial spin labeling].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Association between bronchopulmonary dysplasia and death or neurodevelopmental impairment at 3 years in preterm infants without severe brain injury.Frontiers in neurology · 2023Article
- Retinopathy of prematurity and neurodevelopmental outcomes in preterm infants: A systematic review and meta-analysis.Frontiers in pediatrics · 2023Review
- Motor Optimality Scores are significantly lower in a population of high-risk infants than in infants born moderate-late preterm.Early human development · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Although impaired neurodevelopment is strongly associated with severe brain injury, most preterm infants survive without severe brain injury. In this study, the association of impaired neurodevelopment and neonatal morbidities of preterm infants was assessed after excluding those with severe brain injury. This was a retrospective study of very low birthweight infants in a single tertiary center. After excluding infants with severe brain injury, the study population was categorized as infants without intraventricular hemorrhage (IVH) and with low-grade IVH. Neurodevelopmental outcomes at a corrected age (CA) of 18-24 months were evaluated using the Bayley Scales of Infant and Toddler Development 3rd Edition (Bayley-III). Cerebral palsy (CP), hearing impairment and blindness were also assessed and compared. Of 240 infants, 25 (11.6%) infants had combined neurodevelopmental impairment (NDI). In the multivariate analysis for combined NDI, small for gestational age (SGA) (adjusted OR 6.820, 95% confidence intervals (CI) 1.770-26.307), moderate to severe bronchopulmonary dysplasia (BPD) (aOR 3.21, 95% CI 1.032-9.999) and severe retinopathy of prematurity (ROP) (aOR 5.669, 95% CI 1.132-28.396) were associated with combined NDI. Among neonatal morbidities, moderate to severe BPD and severe ROP were associated with adverse neurodevelopmental outcomes in preterm infants without severe brain injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.