ReviewAudiology research2021
Meta-Analysis-Correlation between Spiral Ganglion Cell Counts and Speech Perception with a Cochlear Implant.
Review in Audiology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Neural Hearing Loss: Mechanisms, Diagnosis and Treatment Horizons.Journal of the Association for Research in Otolaryngology : JARO · 2026Review
- Evaluating the Relationship Between Electrical Dynamic Range and Speech Perception Outcomes in Experienced Post-Lingually Deaf Adult Cochlear Implant Users: A Bicentric Study.Audiology research · 2026Article
- Peripheral Neural Plasticity in Cochlear Implant Users Across the Lifespan.JAMA otolaryngology-- head & neck surgery · 2026Article
- Cochlear neural functional competence: an integrative transcriptomic module analysis of excitability, plasticity and microenvironmental support programs.Frontiers in cellular neuroscience · 2026Article
- The auditory nerve implant-concept and device description of a novel electrical auditory prosthesis.Bioelectronic medicine · 2025Review
- A deep learning framework for understanding cochlear implants.bioRxiv : the preprint server for biology · 2025Article
- Quantifying Residual Hearing Loss from Electrode Insertion Trauma in Cochlear Implant Surgery: A Prospective Double-Blind Study.The journal of international advanced otology · 2025Observational
- Model-Based Inference of Electrode Distance and Neuronal Density from Measured Detection Thresholds in Cochlear Implant Listeners.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- Labyrinthitis ossificans with fluctuating symptoms lasting for more than 10 years: a case report and literature review.Translational pediatrics · 2025Article
- An Electrically Evoked Compound Action Potential Marker for Local Spiral Ganglion Neuron Degeneration: The Failure Index.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Conundrum of Labyrinthitis Ossificans: An Etiology-Based Case Comparison and Review of Literature.Turkish archives of otorhinolaryngology · 2023Article
- Sheep as a large animal model for hearing research: comparison to common laboratory animals and humans.Laboratory animal research · 2023Review
- Cochlear Health and Cochlear-implant Function.Journal of the Association for Research in Otolaryngology : JARO · 2023Review
- "Of mice and men": the relevance of Cometin and Erythropoietin origin for its effects on murine spiral ganglion neuron survival and neurite outgrowthFrontiers in neuroscience · 2023Article
- Changes in the Electrically Evoked Compound Action Potential over time After Implantation and Subsequent Deafening in Guinea Pigs.Journal of the Association for Research in Otolaryngology : JARO · 2022Article
- Adults with cochlear implants can use prosody to determine the clausal structure of spoken sentences.The Journal of the Acoustical Society of America · 2021Article
- Article
- The Failure Index as Marker of the Neural Health Profile in MED-EL CI Users: A Retrospective Analysis.Trends in hearingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The presence of spiral ganglion cells (SGCs) is widely accepted to be a prerequisite for successful speech perception with a cochlear implant (CI), because SGCs provide the only known conduit between the implant electrode and the central auditory system. By extension, it has been hypothesized that the number of SGCs might be an important factor in CI outcomes. An impressive body of work has been published on findings from the laborious process of collecting temporal bones from CI users and counting the number of SGCs to correlate those numbers with speech perception scores, but the findings thus far have been conflicting. We performed a meta-analysis of all published studies with the hope that combining existing data may help us reach a more definitive conclusion about the relationship between SGC count and speech perception scores in adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.