Evidence map›Paper›PMID 34073149›Full record

ArticleCancers2021

The Value of Intraoperative Ultrasound in Selective Lateral Cervical Neck Lymphadenectomy for Papillary Thyroid Cancer: A Prospective Pilot Study.

Giovanna Di Meo, Francesco Paolo Prete, Giuseppe Massimiliano De Luca, Alessandro Pasculli, Lucia Ilaria Sgaramella, Francesco Minerva, Francesco Antonio Logoluso, Giovanna Calculli, Angela Gurrado, Mario Testini

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Giovanna Di MeoUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Francesco Paolo PreteUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Giuseppe Massimiliano De LucaUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Alessandro PasculliUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Lucia Ilaria SgaramellaUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Francesco MinervaUnit of Academic Internal Medicine "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Francesco Antonio LogolusoUnit of Academic Endocrinology, Department of Emergency and Organ Transplantations, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Giovanna CalculliUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Angela GurradoUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.
Mario TestiniUnit of Academic General Surgery "V. Bonomo", Department of Biomedical Sciences and Human Oncology, University of Bari, Polyclinic Hospital, 70124 Bari, Italy.ORCID 0000-0002-9297-4894
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Lymph node metastases from papillary thyroid cancer (PTC) are frequent. Selective neck dissection (SND) is indicated in PTC with clinical or imaging evidence of lateral neck nodal disease. Both preoperative ultrasound (PreUS) and intraoperative palpation or visualization may underestimate actual lateral neck nodal involvement, particularly for lymph-nodes located behind the sternocleidomastoid muscle, where dissection may also potentially increase the risk of postoperative complications. The significance of diagnostic IOUS in metastatic PTC is under-investigated. (2) Methods: We designed a prospective diagnostic study to assess the diagnostic accuracy of IOUS compared to PreUS in detecting metastatic lateral neck lymph nodes from PTC during SND. (3) Results: There were 33 patients with preoperative evidence of lateral neck nodal involvement from PTC based on PreUS and fine-needle cytology. In these patients, IOUS guided the excision of additional nodal compartments that were not predicted by PreUS in nine (27.2%) cases, of which eight (24.2%) proved to harbor positive nodes at pathology. The detection of levels IIb and V increased, respectively, from 9% (PreUS) to 21% (IOUS) (

Indexed as

intra-operative ultrasoundmetastatic papillary thyroid cancerneck dissection

Identifiers

PMID34073149
PMCPMC8198597
OpenAlexW3165866625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.